全麻辅助快速阿片类脱毒的研究进展  

Research progress of the general anesthesia-assisted rapid opioids detoxification

作　　者：徐薇(综述)[1] 罗俊(审校)[1] XU Wei;LUO Jun(West China Hospital of Sichuan University,Chengdu 615000,Sichuan,CHINA)

机构地区：[1]四川大学华西医院麻醉科,四川成都615000

出　　处：《海南医学》2024年第1期149-152,共4页Hainan Medical Journal

摘　　要：全麻辅助快速阿片类脱毒(AAROD)也被称为超快速阿片类脱毒(UROD),是指在全麻状态下给予阿片类药物依赖者清醒状态不能耐受的大剂量阿片类受体拮抗剂,帮助患者在麻醉状态下度过脱毒期,缩短戒断症状时间,减轻患者痛苦。药物依赖脱瘾方法从传统的丁丙诺啡替代疗法、美沙酮替代疗法到AAROD及其改良方法,脱毒成功率不断提高。本文就AAROD的研究进展进行综述。General anesthesia-assisted rapid opioid detoxification(AAROD),also known as ultra rapid opioid detoxification(UROD),refers to the administration of high-dose opioid receptor antagonists that cannot be tolerated by opioid addicts in a conscious state under general anesthesia,helping patients pass the detoxification period under anesthesia,shorten the duration of withdrawal symptoms,and alleviate the pain.From traditional buprenorphine replacement therapy and methadone replacement therapy to the current general anesthesia-assisted rapid opioid detoxification and its improved methods,the success rate of detoxification is constantly improving.This article summarizes the research progress of general anesthesia-assisted rapid opioid detoxification.

关 键 词：全身麻醉 超快速脱毒 纳曲酮 纳洛酮 

分 类 号：R614.2[医药卫生—麻醉学]