妇科疾病患者腹腔镜手术中不同剂量右美托咪定的麻醉效果  

Anesthetic Effects of Different Doses of Dexmedetomidine in Laparoscopic Surgery for Patients with Gynecologic Diseases

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作  者:顾礼萍 GU Liping(Department of Anesthesiology,Yangzhong Hospital of Traditional Chinese Medicine,Yangzhong,Jiangsu Province,212200 China)

机构地区:[1]扬中市中医院麻醉科,江苏扬中212200

出  处:《中外医疗》2023年第32期96-100,共5页China & Foreign Medical Treatment

摘  要:目的 分析右美托咪定剂量差异在妇科疾病患者腹腔镜手术麻醉中的作用。方法 选取2020年1月—2023年8月扬中市中医院麻醉科50例接受腹腔镜手术的妇科疾病患者,患者均经右美托咪定麻醉,根据用药剂量分为两组,每组25例。对照组予以高剂量(0.8μg/kg),观察组予以低剂量(0.4μg/kg),对比两组患者不同阶段血流动力学、麻醉前后血气指标,麻醉后恢复时间。结果 麻醉前,两组患者各项指标比较,差异无统计学意义(P>0.05);观察组麻醉后10 min血压和心率高于对照组,插管时、搭建气腹后15 min和术毕血压和心率低于对照组,差异有统计学意义(P<0.05);观察组搭建气腹15 min后血氧饱和度(92.54±2.68)%、动脉血氧分压(84.42±2.67)mmHg均高于对照组,动脉二氧化碳分压(44.64±2.15)mmHg低于对照组,差异有统计学意义(t=4.049、7.203、11.695,P<0.05);观察组麻醉后恢复时间短于对照组,差异有统计学意义(P<0.05)。结论 低剂量右美托咪定可降低血流动力学波动风险,对血气指标稳定性有良好的维持作用,利于患者麻醉后恢复。Objective To analyze the role of dexmedetomidine dose difference in anesthesia for laparoscopic surgery in patients with gynecological diseases.Methods 50 patients with gynecological diseases who underwent laparoscopic surgery in the Department of Anesthesiology of Yangzhong Hospital of Traditional Chinese Medicine from January 2020 to August 2023 were selected.All patients were anesthetized by dexmedetomidine and divided into two groups according to the dosage with 25 cases in each group.The control group was given a high dose(0.8 μg/kg) and the observation group was given a low dose(0.4 μg/kg).Hemodynamics,blood gas indexes before and after anesthesia,and the recovery time after anesthesia were compared between the two groups.Results Before anesthesia,there was no significant difference in all indexes between the two groups(P>0.05).Blood pressure and heart rate in the observation group were higher than that of the control group 10 min after anesthesia,and the blood pressure and heart rate at the time of intubation,15 min after pneumoperitoneum establishment and after operation were lower than those of control group,the difference was statistically significant(P<0.05).15 min after pneumoperitoneum was established in the observation group,blood oxygen saturation(92.54±2.68) %,arterial blood oxygen partial pressure(84.42±2.67) mmHg were higher than those in the control group,and arterial partial pressure of carbon dioxide(44.64±2.15) mmHg were lower than those in the control group,the differences were statistically significant(t=4.049,7.203,11.695,P<0.05).The recovery time after anesthesia in the observation group was shorter than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Low-dose dexmedetomidine can reduce the risk of hemodynamic fluctuations,has a good maintenance effect on the stability of blood gas indexes,and facilitates the recovery of patients after anesthesia.

关 键 词:腹腔镜手术 右美托咪定 血流动力学 血气指标 

分 类 号:R614[医药卫生—麻醉学]

 

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