固本化瘀周期疗法对围绝经期崩漏患者卵巢功能的影响  

Effect of Periodic Therapy of Cultivating the Vital Essence and Resolving Stasis on Ovarian Function of Patients with Metrorrhagia and Metrostaxis in Perimenopausal Period

作　　者：方圆[1] 叶咏菊[1] 江伟华[1] FANG Yuan;YE Yongju;JIANG Weihua(Department of Obstetrics and Gynecology,Lishui Hospital of Traditional Chinese Medicine,Lishui Zhejiang 323000,China)

机构地区：[1]丽水市中医院妇产科,浙江丽水323000

出　　处：《新中医》2023年第22期100-104,共5页New Chinese Medicine

基　　金：浙江省名老中医专家传承工作室建设项目江伟华名老中医专家传承工作室(GZS2020051)。

摘　　要：目的:观察固本化瘀周期疗法对围绝经期崩漏患者卵巢功能的影响。方法:将符合纳入标准的崩漏患者80例,随机分为治疗组及对照组各40例。对照组予地屈孕酮片治疗,治疗组在对照组治疗方案的基础上予固本化瘀周期疗法治疗。观察2组治疗前后阴道出血情况、卵巢功能变化及复发率。结果:止血疗效总有效率治疗组92.5%,对照组87.5%,差异无统计学意义(P>0.05);2组止血总疗效比较,经曼-惠特尼检验,差异有统计学意义(P<0.05),治疗组疗效优于对照组。治疗后,治疗组基础促卵泡生成素(FSH)、FSH/促黄体生成素(LH)均低于对照组,雌二醇(E2)、抗缪勒管激素(AMH)均高于对照组,差异均有统计学意义(P<0.05),治疗组卵巢功能优于对照组。结论:固本化瘀周期疗法联合地屈孕酮片治疗围绝经期崩漏在止血、改善卵巢功能方面均优于单独应用地屈孕酮片。Objective:To observe the effect of periodic therapy of cultivating the vital essence and resolving stasis on ovarian function and recurrence rates of patients with metrorrhagia and metrostaxis in perimenopausal period.Methods:A total of 80 cases of patients with metrorrhagia and metrostaxis who met the inclusion criteria were randomly divided into the treatment group and the control group,with 40 cases in each group.The control group was treated with Dydrogesterone Tablets,and the treatment group was additionally treated with periodic therapy of cultivating the vital essence and resolving stasis based on the treatment plan of the control group.Vaginal bleeding,changes in ovarian function,and recurrence rates in the two groups were observed before and after treatment.Results:The total effective rate of hemostasis was 92.5%in the treatment group and 87.5%in the control group,there being no significant difference(P>0.05).The total hemostatic effects in the two groups were compared by Mann-Whitney test,the difference being significant(P<0.05),and the curative effect in the treatment group was better than that in the control group.After treatment,the levels of basal follicle-stimulating hormone(FSH)and FSH/luteinizing hormone(LH)in the treatment group were lower than those in the control group,estradiol(E2)and anti-mullerian hormone(AMH)were higher than those in the control group,differences being significant(P<0.05).Conclusion:In the treatment of patients with metrorrhagia and metrostaxis in perimenopausal period,the periodic therapy of cultivating the vital essence and resolving stasis combined with Dydrogesterone Tablets is superior to simple treatment with Dydrogesterone Tablets in hemostasis,improving ovarian function.

关 键 词：崩漏 固本化瘀周期疗法 地屈孕酮片 卵巢功能 抗缪勒管激素 雌二醇 

分 类 号：R271.12[医药卫生—中医妇科学]