Efficacy of surgical resection and ultra-reduced tension suture combined with superficial radiation in keloid treatment  

作　　者：Xiao-Ying Hu Qiao Yang Xiao-Yu Guan Jin-Ying Li Ling-Ling Wang Kun Li Xiao-Tao Zhang 

机构地区：[1]Department of Cosmetic Medicine,Qingdao Eighth People’s Hospital,Qingdao 266100,Shandong Province,China [2]Department of Radiation Oncology,The Affiliated Qingdao Central Hospital of Qingdao University,Qingdao 266042,Shandong Province,China

出　　处：《World Journal of Clinical Cases》2023年第35期8310-8319,共10页世界临床病例杂志

基　　金：This study was reviewed and approved by the Ethics Committee of Qingdao Eighth People’s Hospital(Approval no.:QBYLL-KY-2023-013).

摘　　要：BACKGROUND There are many available treatment options for keloid;however,single treatments are usually less effective.Therefore,more scientifically rational and effective com-bined treatment methods should be sought to solve the pain associated with keloids.AIM To explore the efficacy and safety of surgical resection and ultra-reduced tension suture combined with superficial radiation as keloid treatment.METHODS Fifteen keloid patients admitted to Qingdao Eighth People's Hospital from June 2020 to January 2022 were enrolled in this retrospective analysis.All patients underwent a comprehensive treatment approach comprising surgical resection,ultra-reduced tension suture incision,and superficial radiation therapy within 24 h postoperatively.The modified Vancouver Scar Scale(mVSS)and Patient and Observer Scar Assessment Scale(POSAS)were used to evaluate the treatment effect,whereas the efficacy,adverse effects,and recurrence rate were observed according to the 12-mo follow-up after treatment.RESULTS The mVSS and POSAS scores at 1 and 6 mo after combination treatment decreased compared to before treatment(P<0.001),and the overall response rate was 93.3%.Only one case recurred,yielding a 6.7%recurrence rate.The incidence of local chromour sedimentation rate in 1–3 mo after radiotherapy was 33.3%(5 patients),all subsiding after 6–9 mo,without complications,such as delayed wound healing or dermatitis.CONCLUSION Surgical resection,super subtraction sutures,and superficial radiotherapy are treatment methods with short courses,low recurrence rates,and good safety profiles.

关 键 词：KELOID Ultrasound suture Radiotherapeutics Superficial radiation Ultra-reduced tension suture RADIATION 

分 类 号：R622[医药卫生—整形外科]