Paying attention to the value of thrombelastography and the impact of postreperfusion syndrome on outcomes of liver transplantation  

作　　者：Yu-Li Wu Lu Che Yi-Qi Weng 

机构地区：[1]Department of Anesthesiology,Tianjin First Central Hospital,Tianjin 300192,China

出　　处：《World Journal of Gastroenterology》2023年第46期6092-6094,共3页世界胃肠病学杂志（英文版）

基　　金：Tianjin Anesthesia Research Development Program of Bethune Charitable Foundation,No.TJMZ2022-005;Science Technology Foundation of Tianjin Health Bureau,No.ZC20052.

摘　　要：Only limited information is available about the connection between massive blood transfusion and postoperative survival rates in pediatric liver transplantation.The aim of Gordon's study was to examine the potential impact of perioperative transfusion on postoperative complications and death in young children receiving pediatric living-donor liver transplantation(PLDLT).The authors concluded that transfusion of a red blood cell volume higher than 27.5 mL/kg during the perioperative period is associated with a significant increase in short-and long-term postoperative morbidity and mortality after PLDLT.However,viscoelastic coagulation monitoring was not utilized in the study;instead,only conventional coagulation monitoring was conducted.Overall,the choice of blood coagulation monitoring method during blood transfusion can have a significant impact on patient prognosis.Several studies have shown that the viscoelastic coagulation testing such as thrombelastography(TEG)is highly sensitive and accurate for diagnosing coagulation dysfunction.Indeed,a TEG-guided blood transfusion strategy can improve prognosis.Moreover,postreperfusion syndrome is one of the most common complications of liver transplantation and an important factor affecting the prognosis of patients and should also be included in regression analysis.

关 键 词：Liver transplantation CHILD Blood transfusion THROMBELASTOGRAPHY Reperfusion Injury PROGNOSIS 

分 类 号：R657.3[医药卫生—外科学]