Post-cholecystectomy iatrogenic bile duct injuries:Emerging role for endoscopic management  

作　　者：Mohamed H Emara Mohammed Hussien Ahmed Mohamed I Radwan Emad Hassan Emara Magdy Basheer Ahmed Ali Asem Ahmed Elfert 

机构地区：[1]Department of Hepatology,Gastroenterology and Infectious Diseases,Kafrelsheikh University,Kafr-Elshikh 33516,Egypt [2]Department of Tropical Medicine,Zagazig University,Zagazig 44519,Egypt [3]Department of Diagnostic and Interventional Radiology,Kafrelsheikh University,Kafr-Elshikh 33516,Egypt [4]Department of Surgery,Mansoura University,Mansours 44176,Egypt [5]Department of Emergency,Hargeisa Group Hospital,Hargeisa 1235,Somalia [6]Department of Tropical Medicine,Tanta University,Tanta 33120,Egypt

出　　处：《World Journal of Gastrointestinal Surgery》2023年第12期2709-2718,共10页世界胃肠外科杂志（英文版）（电子版）

摘　　要：Post-cholecystectomy iatrogenic bile duct injuries(IBDIs),are not uncommon and although the frequency of IBDIs vary across the literature,the rates following the procedure of laparoscopic cholecystectomy are much higher than open cholecystectomy.These injuries caries a great burden on the patients,physicians and the health care systems and sometime are life-threatening.IBDIs are associated with different manifestations that are not limited to abdominal pain,bile leaks from the surgical drains,peritonitis with fever and sometimes jaundice.Such injuries if not witnessed during the surgery,can be diagnosed by combining clinical manifestations,biochemical tests and imaging techniques.Among such techniques abdominal US is usually the first choice while Magnetic Resonance Cholangio-Pancreatography seems the most appropriate.Surgical approach was the ideal approach for such cases,however the introduction of Endoscopic Retrograde Cholangio-Pancreatography(ERCP)was a paradigm shift in the management of such injuries due to accepted success rates,lower cost and lower rates of associated morbidity and mortality.However,the literature lacks consensus for the optimal timing of ERCP intervention in the management of IBDIs.ERCP management of IBDIs can be tailored according to the nature of the underlying injury.For the subgroup of patients with complete bile duct ligation and lost ductal continuity,transfer to surgery is indicated without delay.Those patients will not benefit from endoscopy and hence should not do unnecessary ERCP.For low–flow leaks e.g.gallbladder bed leaks,conservative management for 1-2 wk prior to ERCP is advised,in contrary to high-flow leaks e.g.cystic duct leaks and stricture lesions in whom early ERCP is encouraged.Sphincterotomy plus stenting is the ideal management line for cases of IBDIs.Interventional radiologic techniques are promising options especially for cases of failed endoscopic repair and also for cases with altered anatomy.Future studies will solve many unsolved issues in the management o

关 键 词：Iatrogenic bile duct injuries CHOLECYSTECTOMY Surgical repair Endoscopic Retrograde Cholangio-Pancreatography Interventional radiology 

分 类 号：R657.4[医药卫生—外科学]