妊娠期新型冠状病毒感染的垂直传播风险及其与胎儿异常超声表现的相关性探讨  

The risk of vertical transmission of COVID-19 during pregnancy and its correlation with ultrasound abnormal findings in the fetus

作　　者：郭亮雨 张美香 周启昌[2] 王勇军[2] 周后钢[1] 刘静[1] 桑娜[1] 谭婷 李春旺[3] 朱惠娟 姜哲明 谭易涵 骆迎春[1] Guo Liangyu;Zhang Meixiang;Zhou Qichang;Wang Yongjun;Zhou Hougang;Liu Jing;Sang Na;Tan Ting;Li Chunwang;Zhu Huijuan;Jiang Zheming;Tan Yihan;Luo Yingchun(Hunan Provincial Maternal and Child Health Care Hospital,Changsha 410008,China;The second xiangya hospital of central south university,Changsha 410011,China;Hunan Children's Hospital,Chang sha 410007,China)

机构地区：[1]湖南省妇幼保健院,湖南长沙410008 [2]中南大学湘雅二医院,湖南长沙410011 [3]湖南省儿童医院,湖南长沙410007

出　　处：《中国产前诊断杂志（电子版）》2023年第4期27-32,共6页Chinese Journal of Prenatal Diagnosis(Electronic Version)

基　　金：湖南省自然科学基金科卫联合项目(2021JJ70008);湖南省科技成果重点推广计划,湖南省出生缺陷早期预防研究(2019SK1013)。

摘　　要：目的探讨妊娠期新型冠状病毒感染的垂直传播风险及其与胎儿异常超声表现的相关性。方法通过回顾性分析,对2022年12月至2023年1月湖南省妇幼保健院收治的新型冠状病毒感染孕妇及其新生儿的一般资料、产前超声结果及其相关检查进行重点分析。结果2022年12月至2023年1月在湖南省妇幼保健院收治的妊娠合并新型冠状病毒感染的孕妇共547例,有68例新型冠状病毒感染孕妇纳入研究,其中有2例可能存在母婴垂直传播,1例存在母婴垂直传播,并伴有胎儿出现继发性改变的超声表现。结论妊娠期新型冠状病毒感染可能存在罕见的母婴垂直传播风险,并且这可能与胎儿的异常超声表现存在相关性,需引起临床医生与超声医生的充分重视。Objective To investigate the risk of vertical transmission of COVID-19 during pregnancy and its correlation with ultrasound abnormal findings in the fetus.Methods Through retrospective analysis,the general data,prenatal ultrasound results and related examinations of pregnant women with COVID-19,as well as their newborns admitted to Hunan Provincial Maternal and Child Health Care Hospital from December 2022 to January 2023 were analyzed.Results A total of 547 pregnant women with COVID-19 were admitted to Hunan Provincial Maternal and Child Health Care Hospital from December 2022 to January 2023,of which 68 pregnant women with COVID-19 were included in the study,there were 2 cases indicating potential mother-to-child vertical transmission and 1 case confirming mother-to-child vertical transmission,along with ultrasound findings showing secondary changes in the fetus.Conclusion COVID-19 has a rare risk of vertical transmission,and this may be associated with ultrasound abnormal findings in the fetus,which should be paid full attention to by clinicians and sonographers.

关 键 词：新型冠状病毒感染 孕妇 母婴垂直传播 超声 

分 类 号：R445.1[医药卫生—影像医学与核医学] R714.53[医药卫生—诊断学]