潜江地区肥胖儿童骨密度影响因素及与胰岛素抵抗水平的相关性分析  

Influence factors of bone mineral density and its correlation with insulin resistance in obese children in Qianjiang area

作　　者：张超 罗慧 侯波 ZHANG Chao;LUO Hui;HOU Bo(Department of Pediatrics,Jianghan Oilfield General Hospital,Qianjiang,Hubei 433100,China;Department of Endocrinology,Jianghan Oilfield General Hospital,Qianjiang,Hubei 433100,China)

机构地区：[1]江汉油田总医院儿科,湖北潜江433100 [2]江汉油田总医院内分泌科,湖北潜江433100

出　　处：《公共卫生与预防医学》2024年第1期141-144,共4页Journal of Public Health and Preventive Medicine

摘　　要：目的探究潜江地区肥胖儿童骨密度的影响因素及与胰岛素抵抗水平的相关性分析。方法收集2018年1月至2022年12月江汉油田总医院门诊就诊的儿童病例资料,将符合纳入和排除标准的183例肥胖儿童纳入此研究,列为观察组。选择同期352例体检的儿童作为对照组。结果肥胖儿童身体指标包括体重、腰围、腰臀比、BMI均明显高于对照组(P<0.001)。生化指标包括FBG、FINS、Homa-IR、ALP和LDL-C均明显高于对照组(P<0.05),骨密度、Ca、P、sOC和HDL-C明显低于对照组(P<0.001)。肥胖儿童骨密度与其运动强度、阳光照射时长、静坐时间、牛奶及奶制品摄入、甜食摄入、微量元素补充、BMI、Homa-IR和性别呈明显相关性(P<0.05)。BMI、Homa-IR、性别、运动强度和阳光照射时长是影响肥胖儿童骨密度的独立危险因素(P<0.05)。骨密度与BMI、Homa-IR呈负相关(P=0.028&0.017),与运动强度、阳光照射呈正相关(P=0.033)。结论潜江地区肥胖儿童骨密度受性别、体质量指数、膳食及维生素摄入和体力活动等因素影响,同时与胰岛素抵抗呈负相关,Homa-IR可作为肥胖儿童骨密度筛选参考。Objective To explore the influencing factors of bone mineral density(BMD)in obese children in Qianjiang area and analyze the correlation between BMD and insulin resistance.Methods The data on pediatric cases from the outpatient department of Jianghan Oilfield General Hospital in Qianjiang from January 2018 to December 2022 were collected.A total of 183 obese children who met the inclusion and exclusion criteria were included in the study and selected in the observation group.A total of 352 children undergoing physical examination during the same period were selected as the control group.Results The body mass,waist circumference,waist to hip ratio,and BMI of obese children were significantly higher than those of the control group(P<0.001).Biochemical indexes including FBG,FINS,Home-IR,ALP,and LDL-C in obese children were significantly higher than those in the control group(P<0.05),while bone mineral density,Ca,P,sOC and HDL-C were significantly lower than those in the control group(P<0.001).The bone mineral density of obese children was significantly correlated with their exercise intensity,sunshine exposure duration,sitting time,intake of milk and dairy products,intake of sweets,supplementation of trace elements,BMI,Home-IR,and sex(all P<0.05).BMI,Home-IR,sex,exercise intensity,and sunshine exposure length were independent risk factors affecting bone mineral density of obese children(all P<0.05).Bone mineral density was negatively correlated with BMI and Home-IR(P=0.028 and 0.017,respectively),and positive correlation with exercise intensity and sunlight exposure(P=0.033).Conclusion BMD of obese children in Qianjiang area is affected by gender,body mass index,diet,vitamin intake,and physical activity,and is negatively correlated with insulin resistance.Home-IR can be used as a reference for screening BMD of obese children.

关 键 词：儿童 肥胖 骨密度 胰岛素抵抗 

分 类 号：R179[医药卫生—妇幼卫生保健]