含氯消毒剂对人冠状病毒的灭活效果观察  

Observation on the inactivation effect of chlorine disinfectants on human coronavirus

作　　者：陈惠珍[1] 刘冷[1] 王冰姝[1] 钟昱文[1] 郑小凌[1] 王雅静[1] 张磊 纪洵敏 何炽明 邓惠[1] CHEN Hui-zhen;LIU Leng;WANG Bing-shu;ZHONG Yu-wen;ZHENG Xiao-ling;WANG Ya-jing;ZHANG Lei;JI Xu-min;HE Zhi-ming;DENG Hui(Guangdong Provincial Center for Disease Control and Prevention,Guangzhou Guangdong 511430;Guangdong Provincial Institute of Biological Products and Drugs,China)

机构地区：[1]广东省疾病预防控制中心,广东广州511430 [2]广东省生物制品与药物研究所

出　　处：《中国消毒学杂志》2023年第12期881-883,共3页Chinese Journal of Disinfection

基　　金：广东省医学科研基金(B2022330、B2022015)。

摘　　要：目的观察含氯消毒剂对人冠状病毒的灭活效果,为新型冠状病毒的污染消毒提供参考。方法采用悬液定量法,观察含氯消毒剂对人冠状病毒HCoV-229E的灭活效果。结果常温条件下应用含有效氯1000、750和500 mg/L的含氯消毒剂对悬液内的人冠状病毒HCoV-229E分别作用10、20和30 min,能完全灭活该病毒;用有效氯含量≤250 mg/L的含氯消毒剂作用30 min,则不能完全灭活该病毒。结论含氯消毒剂可有效灭活人冠状病毒,但需要确保有效浓度和作用时间。Objective To observe the inactivation effect of chlorine disinfectants on human coronavirus,and to provide reference for contamination disinfection of novel coronavirus.Methods Suspension quantification method was used to observe the inactivation effect of chlorine disinfectants on human coronavirus HCoV-229E.Results Human coronavirus HCoV-229E in suspension was completely inactivated by chlorine-containing disinfectant containing 1000,750 and 500 mg/L available chlorine for 10,20 and 30 min,respectively,at room temperature.The virus could not be completely inactivated by using a chlorine disinfectant with an effective chlorine content≤250 mg/L for 30 min.Conclusion Chlorine disinfectants has good inactivation effect on coronavirus,but the effective concentration and duration of action need to be ensured.

关 键 词：含氯消毒剂 人冠状病毒 灭活效果 

分 类 号：R187.2[医药卫生—流行病学]