某三甲医院药字号肠内营养制剂的使用分析  

Analysis of the application of enteral nutrition drugs in a 3A grade hospital

作　　者：宋戈[1] 张慧峰 鲜瑶[1] 杨雪亮[1] 李卫敏[1] 廖侠[1] SONG Ge;ZHANG Huifeng;XIAN Yao;YANG Xueliang;LI Weimin;LIAO Xia(Department of Nutrition,the First Affiliated Hospital of Xi’an Jiaotong University,Xi’an 710061,China)

机构地区：[1]西安交通大学第一附属医院营养科,西安710061

出　　处：《西北药学杂志》2024年第1期197-200,共4页Northwest Pharmaceutical Journal

基　　金：国家自然科学基金青年基金项目(编号:82203047);杨凌本真基金会横向课题(编号:HX202225)。

摘　　要：目的分析西安市某三甲医院药字号肠内营养制剂的使用情况,为临床合理使用药字号肠内营养制剂提供参考。方法从该院信息管理系统(hospital information system,HIS)中提取2019年至2021年药字号肠内营养制剂的用药数据,对全院药字号营养制剂的销售情况及构成比、用药频度(defined daily doses,DDDs)、限定日费用(defined daily cost,DDC)等药物经济学指标以及各科室使用量进行回顾性统计分析。结果该院肠内营养制剂使用量2019年至2020年呈增长趋势,但2021年度有所下降。DDDs排名前3的制剂分别是百普力、能全素和瑞素。DDC排序前3的制剂是瑞先、百普素和百普力。肝胆外科3年间短肽类制剂使用量位居第1,整蛋白制剂使用量前3的科室分别是神经内科、重症医学科和康复科。结论该院肠内营养制剂平均年使用量偏低,肠内营养与肠外营养治疗比例不均衡。整蛋白制剂瑞先价格较高,患者经济负担重,肠内营养制剂应保质保效,同时应降低价格。临床肠内营养治疗率远低于实际营养不良反应发生率,营养科需进一步加强与临床科室的沟通协作,提高住院患者肠内营养治疗比例。Objective To investigate the utilization of enteral nutrition drugs in a 3A grade hospital,to offer scientific reference for the clinical rational application of enteral nutrition drugs.Methods The medication data of enteral nutrition drugs from 2019 to 2021 were extracted from hospital information system(HIS)system of the hospital,and the pharmacoeconomic indicators such as the sales situation and composition ratio,defined daily doses(DDDs)and defined daily cost(DDC)of enteral nutrition drugs in the whole hospital,as well as the consumption situation of each clinical department were analyzed retrospectively.Results The amount of enteral nutrition in the hospital increased from 2019 to 2020,but decreased in 2021.The top 3 preparations in the list of DDDs were peptisorb liquid,nutrison and fresubin.The top 3 preparations in DDC ranking were fresubin energy fiber,peptisorb and peptisorb liquid.The department of hepatobiliary Surgery ranked first in the consumption of peptide-based enteral nutrition in the 3 years,and the department of neurology,the department of critical care medicine and the department of rehabilitation ranked top 3 in the consumption of intact protein enteral nutrition.Conclusion The average annual use of enteral nutrition in this hospital is low,and the proportion of enteral nutrition and parenteral nutrition treatment is not balanced,which should be paid much attention.The price of enteral nutrition should be reduced to relieve the burden of patients with maintaining the quality and effects.The clinical enteral nutrition treatment rate is far lower than the actual incidence of malnutrition.The department of nutrition needs to further strengthen the communication and cooperation with clinical departments,increase the rate of in-hospital nutritional risk screening,improve the proportion of enteral nutrition treatment of inpatients.

关 键 词：肠内营养制剂 短肽型制剂 整蛋白型制剂 用药频度 限定日费用 

分 类 号：R969.3[医药卫生—药理学]