梅花针叩刺联合中药熏蒸治疗急性痛风性关节炎临床研究  

Clinical Study on Plum-Blossom Needle Tapping Combined with Chinese Medicine Fumigation for Acute Gouty Arthritis

作　　者：王丽琴 刘鸿 卓和伟 WANG Liqin;LIU Hong;ZHUO Hewei(Lishui Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University,Lishui Zhejiang 323000,China)

机构地区：[1]浙江中医药大学附属丽水市中医院,浙江丽水323000

出　　处：《新中医》2023年第23期185-189,共5页New Chinese Medicine

基　　金：浙江中医药大学校级科研项目(2021FSYYZQ08)。

摘　　要：目的:观察梅花针叩刺联合中药熏蒸治疗急性痛风性关节炎(AGA)的临床疗效。方法:将116例AGA湿热蕴结证患者按随机数字表法分成对照组和观察组各58例。对照组采用秋水仙碱片治疗,观察组在对照组基础上进行中药熏蒸联合梅花针叩刺治疗,2组均治疗7 d。比较2组治疗前后关节疼痛视觉模拟评分法(VAS)评分、中医证候积分、实验室指标[血尿酸、血沉(ESR)、血C-反应蛋白(CRP)、白细胞介素-1(IL-1)],比较2组临床疗效及治疗期间发生的不良反应。结果:治疗后观察组总有效率93.10%,高于对照组77.59%(P<0.05)。治疗后,2组关节VAS评分降低(P<0.05),且观察组低于对照组(P<0.05)。治疗后,2组主症、次症中医证候积分均下降(P<0.05),且观察组低于对照组(P<0.05)。治疗后,2组血尿酸、ESR、CRP、IL-1水平均降低(P<0.05),且观察组低于对照组(P<0.05)。2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:梅花针叩刺联合中药熏蒸治疗AGA湿热蕴结证可提高临床疗效,降低炎症反应,且安全性较好。Objective:To observe the clinical effect of plum-blossom needle tapping combined with Chinese medicine fumigation for acute gouty arthritis(AGA).Methods:A total of 116 patients with AGA with retention of damp-heat syndrome were divided into the control group and the observation group according to the random number table method,with 58 cases in each group.The control group was treated with Colchicine Tablets,and the observation group was treated with Chinese medicine fumigation combined with plum-blossom needle tapping based on the treatment of the control group.Both groups were treated for 7 days.The visual analogue scale(VAS)scores,traditional Chinese medicine(TCM)syndrome scores,and laboratory indicators[uric acid,erythrocyte sedimentation rate(ESR),C-reactive protein(CRP),and interleukin-1(IL-1)]were compared between the two groups before and after treatment.The clinical effects and adverse reactions that occurred during treatment were compared between two groups.Results:After treatment,the total effective rate was 93.10%in the observation group,higher than that of 77.59%in the control group(P<0.05).After treatment,the VAS scores in the two groups were decreased(P<0.05),and the score in the observation group was lower than that in the control group(P<0.05).After treatment,the traditional Chinese medicine syndrome scores of the main and secondary symptoms in the two groups were decreased(P<0.05),and the scores in the observation group were lower than those in the control group(P<0.05).After treatment,the levels of blood uric acid,ESR,CRP,and IL-1 in the two groups were decreased(P<0.05),and the levels in the observation group were lower than those in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:The combination of plum-blossom needle tapping and Chinese medicine fumigation for AGA with retention of damp-heat syndrome can improve clinical effects,reduce inflammatory reactions,and have good safety.

关 键 词：急性痛风性关节炎 梅花针 湿热蕴结证 四妙散 中药熏蒸 

分 类 号：R246.1[医药卫生—针灸推拿学]