20例儿童脓癣临床特征分析  

Clinical analysis of 20 cases of kerion in children

作　　者：崔祥祥 郑冰洁 陈茜岚 杨芸 周行 钱秋芳 CUI Xiangxiang;ZHENG Bingjie;CHEN Xilan;YANG Yun;ZHOU Xing;QIAN Qiufang(Department of Dermatology,Shanghai Children’s Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200062,China)

机构地区：[1]上海交通大学医学院附属儿童医院皮肤科,上海200062

出　　处：《中国真菌学杂志》2023年第5期401-405,共5页Chinese Journal of Mycology

基　　金：上海市儿童医院院级课题(2020YLYM01)。

摘　　要：目的探讨分析儿童脓癣的临床特征,以提高临床医师对儿童脓癣的认识。方法回顾性分析2017—2022年我院确诊的20例儿童脓癣患儿的临床资料、治疗和预后。结果20例脓癣中,单发脓肿型17例,多发毛囊炎型3例。19例饲养过猫、犬或兔子,1例有足癣接触史。经口服盐酸特比萘芬片联合口服糖皮质激素和抗生素再辅以外用药物治疗,所有患儿在6~12周内临床治愈。1例有胃部不适,余未见不良反应。3例伴有癣菌疹。结论儿童脓癣临床表现有时不典型,容易误诊。真菌荧光染色直接镜检阳性率高。脓癣培养的病原真菌以犬小孢子菌最常见,其次为须癣毛癣菌。盐酸特比萘芬片治疗脓癣预后较好,安全有效。Objective To explore and analyze the clinical characteristics of kerion in children in order to improve the clinician's understanding of pediatric kerion.Methods The clinical data,treatment and prognosis of 20 cases of children with kerion diagnosed in our hospital from 2017 to 2022 were retrospectively analyzed.Results Among the 20 cases of kerion,17 cases of single abscess type and 3 cases of multiple folliculitis type.Cats,dogs and rabbits were kept in 19 cases,1 case had contact history with tinea pedis.After oral terbinafine hydrochloride combined with oral glucocorticoids and antibiotics,as well as topical antifungal drugs,all the children were clinically cured within 6-12 weeks.One case had stomach discomfort and no adverse reactions were observed.3 cases were accompanied by ringworm rash.Conclusions The clinical manifestations of kerion in children are sometimes atypical and easy to be misdiagnosed.The positive rate of fungal fluorescence staining was high.Microsporum canis was the most common pathogenic fungi in the culture of pyophyton,followed by Trichophyton mentagrophytes.Terbinafine hydrochloride tablet is safe and effective in the treatment of kerion.

关 键 词：儿童 脓癣 犬小孢子菌 须癣毛癣菌 特比萘芬 

分 类 号：R756.1[医药卫生—皮肤病学与性病学]