酸藤子研究进展及质量标志物的预测分析  

Research Progress on Suan Teng Zi and Prediction Analysis of Quality Markers

作　　者：韩沙 陈雅思 谢凤凤 张淼[1] 黄茂春[1,2] 龚志强[1,2] HAN Sha;CHEN Yasi;XIE Fengfeng;ZHANG Miao;HUANG Maochun;GONG Zhiqiang(Key Laboratory of Zhuang Yao Medicine,Guangxi University of Chinese Medicine,Nanning 530200,China;Sainz New School of Medicine,Guangxi University of Chinese Medicine,Nanning 530222,China)

机构地区：[1]广西中医药大学广西壮瑶药重点实验室,广西南宁530200 [2]广西中医药大学赛恩斯新医药学院,广西南宁530222

出　　处：《陕西中医药大学学报》2024年第1期133-138,共6页Journal of Shaanxi University of Chinese Medicine

基　　金：国家重点研发资助项目(2019YFC1712305);广西壮族自治区科技厅“广西壮瑶药重点实验室”科研项目(22-035-25);广西中医药大学赛恩斯新医药学院(国家级)大学生创新创业项目(202113643017)。

摘　　要：酸藤子Embelia laeta(L.)Mez为紫金牛科酸藤子属植物,属于传统瑶药七十二风类,具有应用历史悠久、药用价值高、植物资源丰富、开发前景广阔等优点。酸藤子含有多种类型化合物如黄酮类、醌类、苷类、酚酸、有机酸、生物碱、挥发油等。酸藤子全株均可入药,药理活性筛选表明酸藤子具有抑菌、抗炎、抗氧化等作用。现基于质量标志物(Q-Marker)的理论与研究方法,基于近年来对酸藤子化学成分和药理作用的报道文献,从酸藤子传统药性药效、配伍和化学成分可测性等方面进行质量标志物的预测分析。Embelia laeta(L.)Mez is a plant of the family Ceratophoraceae,belonging to the traditional Yao medicine 72 wind class.It has a long history of application,high medicinal value,abundant plant resources,and broad development prospects.Suan Teng Zi contain various types of compounds such as flavonoids,quinones,glycosides,phenolic acids,organic acids,alkaloids,volatile oils,etc.The entire plant of Suan Teng Zi can be used as medicine,and pharmacological activity screening shows that Suan Teng Zi has antibacterial,anti-inflammatory,antioxidant and other effects.Based on the theory and research methods of Quality Markers(Q-Markers),and based on recent reports on the chemical composition and pharmacological effects of Suan Teng Zi,this study predicts and analyzes the quality markers from the aspects of traditional medicinal properties,efficacy,compatibility,and measurability of chemical components.

关 键 词：酸藤子 化学成分 药理作用 质量标志物 

分 类 号：R29[医药卫生—民族医学]