子午流注择时电温针联合双补增津汤治疗结肠慢传输型便秘气阴两虚证的疗效观察  

Observation on the Therapeutic Effect of Timed Electroacupuncture Combined with Shuangbu Zengjin Decoction in the Treatment of Slow Transit Constipation of the Colon with Qi Yin Deficiency Syndrome

作　　者：周艳阳[1] 陈立平[1] 郭海霞 李阳 ZHOU Yanyang;CHEN Liping;GUO Haixia;LI Yang(The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,China)

机构地区：[1]河南中医药大学第一附属医院,河南郑州450000

出　　处：《中医药信息》2024年第1期59-64,78,共7页Information on Traditional Chinese Medicine

基　　金：河南省中医药科学研究专项课题(2021JDZY041,2022JDZX020);全国名老中医学术经验传承工作室项目(国中医药人教发[2013]47号)。

摘　　要：目的:观察子午流注择时电温针联合双补增津汤治疗结肠慢传输型便秘(STC)气阴两虚证的临床疗效。方法:选择符合纳入标准的152例STC气阴两虚证患者,按随机抽取法分为对照组(枸橼酸莫沙必利治疗)、电针组(枸橼酸莫沙必利+子午流注择时电温针治疗)、中药组(枸橼酸莫沙必利+双补增津汤治疗)和结合组(枸橼酸莫沙必利+子午流注择时电温针+双补增津汤治疗),每组各38例,均治疗4周。观察比较4组患者治疗前后中医症状积分和总积分、结肠传输试验标志物含量、肠道菌群数量、焦虑自评量表评分(SAS)、抑郁自评量表评分(SDS)、慢性便秘严重度评分(CSS)的变化情况,比较临床疗效及随访6个月复发率。结果:4组患者治疗后中医症状积分和总积分、结肠传输试验标志物含量和SAS、SDS、CSS评分均较治疗前比较均明显下降(P<0.05),肠道内大肠埃希数量与治疗前比较明显减少(P<0.05),双歧杆菌、乳酸杆菌数量与治疗前比较明显增多(P<0.05);结合组临床疗效明显优于其他3组(P<0.05),随访期复发率明显低于其他3组(P<0.05)。结论:子午流注择时电温针联合双补增津汤治疗STC气阴两虚证的疗效显著,二者可发挥协同增效作用,能有效缓解便秘症状,调节肠道菌群,恢复肠道运动功能,改善焦虑、抑郁心理状态,降低复发率。Objective:To observe the therapeutic effect of midnight-midday ebb flow electric warming acupuncture combined with Shuangbu Zengjin Decoction(SZD)in the treatment of slow transit constipation(STC)of the colon with qi yin deficiency syndrome.Methods:A hundred and fifty-two patients with STC and qi and yin deficiency syndrome were randomly divided into a control group(mosapride citrate),an electroacupuncture group(mosapride citrate+midnight-midday ebb flow warming acupuncture),a traditional Chinese medicine(TCM)group(mosapride citrate+SZD),and a combination group(Mosapride Citrate+midnight-midday ebb flow warming acupuncture+SZD),with 38 patients in each group,for 4 weeks.Symptom score,content of colonic transmission test markers,gut microbiota,self rating anxiety scale score(SAS),self rating depression scale score(SDS),and chronic constipation severity score(CSS)before and after treatment were observed and compared.The treatment efficiency of the four groups was compared and follow-up time was 6 weeks.Result:After treatment,the TCM symptom score,colonic transit test marker content,SAS score,SDS score,and CSS score of the four groups significantly decreased(P<0.05),and the number of Escherichia coli in the intestine significantly decreased(P<0.05).The number of bifidobacteria and lactobacillus significantly increased(P<0.05),the clinical effect of the combination group was significantly better than that of the other 3 groups(P<0.05),and the recurrence rate during the follow-up period was significantly lower than that of the other 3 groups(P<0.05).Conclusion:The therapeutic effect of midnight-midday ebb flow warming acupuncture combined with Shuangbu Zengjin Decoction on STC with qi and yin deficiency syndrome is significant;the combination of the acupuncture and the decoction can play a synergistic role,can effectively relieve constipation symptoms,regulate intestinal flora,restore intestinal motor function,improve anxiety and depression psychological state,and reduce recurrence rate.

关 键 词：子午流注择时 电温针 双补增津汤 STC 气阴两虚证 复发 

分 类 号：R256.35[医药卫生—中医内科学]