氢气在呼吸系统疾病中的作用及研究进展  

Role of hydrogen in respiratory diseases and research progress

作　　者：李利 朱星星 张毅[3] 商艳[1,3] LI Li;ZHU Xingxing;ZHANG Yi;SHANG Yan(Department of Respiratory and Critical Care Medicine,The First Affiliated Hospital of Naval Medical University(Second Military Medical University),Shanghai 200433,China;Department of Respiratory and Critical Care Medicine,People’s Hospital of Haining,Haining 314400,Zhejiang,China;Department of General Practice,The First Affiliated Hospital of Naval Medical University(Second Military Medical University),Shanghai 200433,China)

机构地区：[1]海军军医大学(第二军医大学)第一附属医院呼吸与危重症医学科,上海200433 [2]海宁市人民医院呼吸与危重症医学科,海宁314400 [3]海军军医大学(第二军医大学)第一附属医院全科医学科,上海200433

出　　处：《海军军医大学学报》2024年第1期74-79,共6页Academic Journal of Naval Medical University

基　　金：国家自然科学基金(82170033);上海市自然科学基金(21ZR1479200);上海市“社区医学与健康管理科研课题研究”专项基金(2023SQ01);上海市虹口区卫生健康委员会医学科研课题(虹卫2302-43);浙江省基础公益计划项目(LQ22H010001)。

摘　　要：氢气是一种无色无味、具有生物活性的还原性小分子气体,具有抗炎、抗氧化、抗凋亡等生物学功能,可用于多种疾病的辅助治疗。人们使用氢的方式已不局限于氢气吸入,还出现了氢水饮用、含氢溶液注射、含氢透析液透析等新方法,氢的生物学作用得到广泛关注。本文围绕氢气在慢性阻塞性肺疾病、哮喘、肺癌、新型冠状病毒感染、急性肺损伤、肺纤维化等呼吸系统疾病中的作用及研究进展进行讨论。Hydrogen is a colorless,odorless,and bioactive reducing small molecule gas with anti-inflammatory,antioxidant,anti-apoptosis,and other biological functions,and it can be used in the adjuvant treatment of a variety of diseases.The application of hydrogen is not only for inhalation,but also for hydrogen water drinking,hydrogen solution injection,hydrogen dialysate dialysis,etc.,and its biological role has been widely studied.This article reviews the role of hydrogen in chronic obstructive pulmonary disease,asthma,lung cancer,coronavirus disease 2019,acute lung injury,pulmonary fibrosis,and other respiratory diseases,and discusses the recent research progress.

关 键 词：氢气 呼吸系统疾病 慢性阻塞性肺疾病 哮喘 肺癌 新型冠状病毒感染 急性肺损伤 肺纤维化 

分 类 号：R56[医药卫生—呼吸系统]