福建省美沙酮维持治疗患者脱失情况及影响因素  

Dropout and influencing factors in methadone maintenance treatment patients in Fujian Province

作　　者：林毅翔 吴韶彬[1] 谢剑锋[1] LIN Yixiang;WU Shaobin;XIE Jianfeng(Fujian Provincial Center for Disease Control and Prevention,Fuzhou 350000.Fuyjian,China)

机构地区：[1]福建省疾病预防控制中心,福州350000

出　　处：《中国艾滋病性病》2023年第12期1348-1351,共4页Chinese Journal of Aids & STD

摘　　要：目的了解和掌握福建省美沙酮维持治疗(MMT)门诊脱失情况,探究其影响因素,为今后降低脱失率、开展针对性干预工作提供参考。方法采用回顾性研究,资料来源为戒毒药物维持治疗数据信息管理系统,研究对象为2006―2022年在福建省进行MMT的患者,使用SPSS 21.0进行数据库整理和分析,单因素分析采用χ^(2)检验,多因素分析采用二元Logistic回归分析。结果共纳入MMT患者7790名,脱失人数7278名,脱失率为93.43%。入组年龄为≥60岁组(OR=0.223,95%CI:0.077~0.644)、治疗时间大于6个月(OR=0.205,95%CI:0.135~0.312)、日平均治疗剂量大于60 mL(OR=0.674,95%CI:0.545~0.832)的患者脱失风险更低;少数民族(OR=1.799,95%CI:1.015~3.188)、乘坐公共交通工具来门诊(OR=1.459,95%CI:1.068~1.993)的患者脱失风险更高。结论福建省MMT门诊脱失率较高,应加强对低龄、新入组患者的社会支持、心理指导工作,加强MMT服务可及性,合理制定维持治疗剂量,以降低脱失率,提高MMT治疗效果。Objective To comprehend the outpatient dropout of methadone maintenance therapy(MMT)in Fujian Province and explore its influencing factors,so as to provide a reference for reducing the dropout rates and targeting specific interventions in the future.Methods A retrospective analysis of maintenance therapy for drug rehabilitation was conducted using the Drug Maintenance Treatment Data Information Management System.The study involved patients who underwent MMT in Fujian Province from 2006 to 2022.The data was sorted and analyzed using SPSS 21.0 software.Chi-square test and binary logistic regression were used for univariate and multivariate analysis,respectively.Results A total of 7790 patients were recruited for this study,with a subsequent dropout of 7278 cases resulting in a dropout rate of 93.43%.Patients who aged≥60 years old(OR=0.223,95%CI:0.077-0.644),had a treatment duration of more than 6 months(OR=0.205,95%CI:0.135-0.312),and had an average daily dose of more than 60 mL(OR=0.674,95%CI:0.545-0.832)showed a lower risk of dropout.Whereas,patients who identified as ethnic minorities(OR=1.799,95%Cl:1.015-3.188)and those who relied on public transportation to attend outpatient clinics(OR=1.459,95%Cl:1.068-1.993)exhibited a higher risk of dropout.Conclusions The dropout rate of MMT in outpatient clinics in Fujian Province is relatively high.It is necessary to strengthen social support and provide psychological guidance for young and newly enrolled patients.Furthermore,it is imperative to increase accessibility to MMT services and develop rationally formulating of maintenance dose to decrease the dropout rates and enhance the efficiency of MMT.

关 键 词：美沙酮维持治疗 脱失 影响因素 

分 类 号：R512.91[医药卫生—内科学]