加味复方三七颗粒治疗稳定型心绞痛肾虚血瘀证临床观察  

Efficacy observation of modified compound Sanqi granule on stable angina pectoris with syndrome of kidney deficiency and blood stasis

作　　者：华杨 姚淮芳[1] HUA Yang;YAO Huai-fang(The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Hefei230031,China)

机构地区：[1]安徽中医药大学第一附属医院,合肥230031

出　　处：《山西中医》2024年第1期9-12,共4页Shanxi Journal of Traditional Chinese Medicine

基　　金：安徽中医药大学第一附属医院临床科学研究项目(编号:2020yfyzc04)。

摘　　要：目的:观察加味复方三七颗粒治疗稳定型心绞痛肾虚血瘀证临床疗效。方法:纳入稳定型心绞痛肾虚血瘀证患者64例,随机分为两组各32例。对照组予常规西医治疗,治疗组在对照组基础上予加味复方三七颗粒,两组均治疗4周。比较两组治疗后中医证候积分、中医证候疗效、心绞痛发作时间及频率、心电图疗效、硝酸甘油减停率及血液流变学指标。结果:治疗组中医证候疗效为90.63%,优于对照组的75.00%(P<0.05);治疗组心电图疗效为87.50%,优于对照组的68.75%(P<0.05)。两组中医证候积分、心绞痛发作频率及时间、血液流变学相关指标水平均不同程度下降,治疗组较对照组下降更明显(P<0.05);治疗组硝酸甘油停减率为90.63%,优于对照组的75.00%(P<0.05);两组均无不良反应发生。结论:加味复方三七颗粒治疗稳定型心绞痛肾虚血瘀证患者临床效果显著,安全有效。Objective:To observe the clinical efficacy of modified compound Sanqi granule on stable angina pectoris with syndrome of kidney deficiency and blood stasis.Methods:64 cases of patients with stable angina pectoris with syndrome of kidney deficiency and blood stasis were randomly divided into two groups,32 cases in each group.The control group was treated with routine western medicine,while the treatment group was treated plus with modified compound Sanqi granule on the basis of control group.Both groups were treated for 4 weeks.TCM syndrome score,efficacy of TCM syndrome,time and frequency of angina pectoris attack,ECG efficacy,stopping or reducing rate of nitroglycerin and hemorheological indexes were compared between two groups after treatment.Results:The efficacy of TCM syndrome of treatment group was 90.63%,which was better than 75.00%of control group(P<0.05).ECG efficacy of treatment group was 87.50%,which was better than 68.75%of control group(P<0.05).TCM syndrome score,frequency and time of angina pectoris attack and levels of related hemorheological indexes were all decreased to different degrees in two groups,and the decrease of treatment group was more obvious than that of control group(P<0.05).The stopping or reducing rate of nitroglycerin was 90.63%in treatment group,which was better than 75.00%in control group(P<0.05).No adverse reactions occurred in both groups.Conclusion:The clinical efficacy of modified compound Sanqi granule on stable angina pectoris with syndrome of kidney deficiency and blood stasis is better.

关 键 词：稳定型心绞痛 肾虚血瘀 加味复方三七颗粒 中医药疗法 

分 类 号：R541[医药卫生—心血管疾病]