中药联合聚焦超声消融手术治疗子宫肌瘤临床观察  

Efficacy observation of Chinese herbal medicine and focused ultrasound ablation on hysteromyoma

作　　者：张代碧[1] 吴敏 雷婷婷 李晓辉 何玉春 冉峰 代艳[2] 周义杰 张亚楠 王幸栓[1] ZHANG Dai-bi;WU Min;LEI Ting-ting(Suining Hospital of Traditional Chinese Medicine,Sichuan Province,Suining 629000,China;不详)

机构地区：[1]四川省遂宁市中医院,遂宁629000 [2]川北医学院 [3]成都中医药大学

出　　处：《山西中医》2024年第1期15-18,共4页Shanxi Journal of Traditional Chinese Medicine

基　　金：四川省中医药管理局科学技术研究专项课题项目(编号:2020LC0220)。

摘　　要：目的:观察中药联合聚焦超声消融手术治疗子宫肌瘤的近期和远期疗效,以及对生殖激素的影响。方法:选取拟行聚焦超声消融手术(FUAS)的子宫肌瘤患者86例为研究对象,治疗组45例予FUAS联合中药治疗,对照组41例单纯予FUAS。另选行全子宫切除术的子宫肌瘤患者29例为切除术组。比较对照组与切除术组治疗前后生殖激素变化,比较治疗组与对照组子宫肌瘤体积变化、PBAC评分。结果:术后对照组FSH、LH、E2水平与术前比较无统计学差异(P>0.05),切除术组FSH、LH水平较术前有所升高(P<0.05)。术后治疗组与对照组子宫肌瘤总体积较术前均明显缩小,治疗组较对照组肌瘤缩小更显著;两组月经PBAC评分较术前均有明显降低(P<0.05)。结论:聚焦超声消融手术治疗子宫肌瘤能有效缩小肌瘤体积,对患者卵巢内分泌功能无明显影响。中药联合FUAS能够更有效缩小肌瘤体积,改善月经量和临床症状。Objective:To observe the short-term and long-term efficacy of Chinese herbal medicine and focused ultrasound ablation on hysteromyoma and its effects on reproductive hormones.Methods:86 cases of patients with hysteromyoma who were treated by focused ultrasound ablation(FUAS)were selected as the researched objects.45 cases of treatment group were treated with FUAS and Chinese herbal medicine,while 41 cases of control group were treated with FUAS alone.Other 29 cases of patients with hysteromyoma who were treated by total hysterectomy were selected as resection group.The changes of reproductive hormones were compared between control group and resection group before and after treatment.The volume changes of hysteromyoma and PBAC scores were compared between treatment group and control group.Results:After operation,the levels of FSH,LH and E2 of control group were compared with before operation,the difference was not statistically significant(P>0.05),while the levels of FSH and LH of resection group were higher than those before operation(P<0.05).After operation,the total volume of hysteromyoma in treatment group and control group was significantly reduced compared with before operation,and the reduction of hysteromyoma in treatment group was more significant than in control group.The menstrual PBAC scores in both groups were significantly lower than before operation(P<0.05).Conclusion:Focused ultrasound ablation for treating hysteromyoma can effectively reduce the volume of hysteromyoma,and has no obvious effect on ovarian endocrine function.Chinese herbal medicine and FUAS can more effectively reduce the volume of myoma,and improve menstrual blood volume and clinical symptoms.

关 键 词：子宫肌瘤 聚焦超声消融术 中西医结合疗法 

分 类 号：R711.74[医药卫生—妇产科学]