机构地区:[1]复旦大学附属金山医院肿瘤科,上海201508 [2]复旦大学护理学院,上海200032 [3]复旦大学附属金山医院预防保健科,上海201508
出 处:《中国实用护理杂志》2024年第1期27-33,共7页Chinese Journal of Practical Nursing
摘 要:目的探讨多学科营养支持小组对肺癌化疗患者营养状况及生命质量的影响,为肺癌化疗患者营养干预方案的制订提供参考。方法采用类实验研究方法,便利抽样选取2021年2月至2022年7月就诊于复旦大学附属金山医院的74例肺癌化疗患者为研究对象。按照入院时间将2021年2—8月收治的37例患者设为对照组,给予常规护理干预;将2021年9月至2022年7月收治的37例患者设为观察组,给予多学科营养支持小组模式干预。干预时间为3个化疗周期,比较2组患者干预前后血清营养学指标及生命质量变化的差异。结果对照组男27例,女10例,年龄(68.14±6.82)岁;观察组男30例,女7例,年龄(65.92±9.17)岁。2组患者干预前血清营养学指标及生命质量比较差异均无统计学意义(均P>0.05)。观察组患者干预后血清总蛋白、白蛋白、前白蛋白含量分别为(69.41±5.87)、(38.11±4.04)g/L和(243.57±67.58)mg/L,高于对照组的(65.54±8.33)、(35.78±5.39)g/L和(200.84±60.84)mg/L,差异均有统计学意义(t=-2.31、-2.10、-2.86,均P<0.05)。观察组患者干预后情绪功能、整体健康/生命质量的评分分别为(88.29±16.72)、(60.36±13.24)分,高于对照组的(76.80±17.58)、(46.40±16.38)分;疲倦、恶心呕吐、失眠、食欲丧失症状领域的评分分别为(34.53±22.19)、(11.26±8.83)、(20.72±16.39)、(24.32±18.67)分,低于对照组的(45.65±22.95)、(25.68±18.67)、(36.94±23.29)、(40.54±22.41)分,差异均有统计学意义(t值为-4.03~4.24,均P<0.05)。结论在肺癌患者化疗期间,实施多学科营养支持小组可以显著改善患者的营养状况,提高患者生命质量。Objective To explore the effects of multi-disciplinary nutrition support team on nutritional status and quality of life in lung cancer patients undergoing chemotherapy,so as to provide reference for the formulation of nutritional intervention plans for lung cancer patients undergoing chemotherapy.Methods This was a quasi experimental study.A total of 74 patients with lung cancer undergoing chemotherapy in Jinshan Hospital of Fudan University from February 2021 to July 2022 were selected as the research object by convenient sampling method.They were divided into two groups according to their admission time,37 cases of patients from February to August 2021 for the control group,using conventional nursing interventions,37 cases of patients from September 2021 to July 2022 for the observation group,with multi-disciplinary nutrition support team.A follow-up was conducted for three chemotherapy cycles,serum nutrition indicators and quality of life were compared between the two groups.Results There were 27 males and 10 females in the control group,aged(68.14±6.82)years old.There were 30 males and 7 females in the observation group,aged(65.92±9.17)years old.There was no significant difference in the serum nutrition indicators and quality of life before intervention between the two groups(all P>0.05).The serum total protein,albumin and prealbumin levels in the observation group were(69.41±5.87),(38.11±4.04)g/L,and(243.57±67.58)mg/L,which were higher than those in the control group(65.54±8.33),(35.78±5.39)g/L,and(200.84±60.84)mg/L,the differences were statistically significant(t=-2.31,-2.10,-2.86,all P<0.05).After intervention,the observation group showed higher scores for emotional function and overall health/life quality,with(88.29±16.72),(60.36±13.24)points,compared to the control group with(76.80±17.58),(46.40±16.38)points.The scores for fatigue,nausea/vomiting,insomnia,and loss of appetite were(34.53±22.19),(11.26±8.83),(20.72±16.39),(24.32±18.67)points in the observation group,which were lower than th
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