肺表面活性物质治疗新生儿急性呼吸窘迫综合征的研究进展  

A Review of Pulmonary Surfactant in Treating Neonatal Acute Respiratory Distress Syndrome

作　　者：王劲 王丹(综述)[1] 曾凌空(审校)[1] WANG Jin;WANG Dan;ZENG Lingkong(Department of Neonatology,Wuhan Children's Hospital(Wuhan Maternal and Child Healthcare Hospital),Tongji Medical College,Huazhong University of Science&Technology,Wuhan 430016,Hubei,China)

机构地区：[1]华中科技大学同济医学院附属武汉儿童医院(武汉市妇幼保健院)新生儿内科,湖北武汉430016

出　　处：《江汉大学学报（自然科学版）》2024年第1期72-79,共8页Journal of Jianghan University：Natural Science Edition

摘　　要：新生儿急性呼吸窘迫综合征(nARDS)是新生儿期严重疾病之一,严重危害新生儿健康,其主要治疗手段包括呼吸机辅助通气、PS替代、抗感染及营养支持等。PS的替代治疗是新生儿急性呼吸窘迫综合征的独特治疗方式之一,PS的使用能显著改善患儿的低氧血症和呼吸窘迫。本文就nARDS的治疗过程中,PS的种类、剂量、给药途径、给药时机、重复给药等方面作一综述。Neonatal acute respiratory distress syndrome(nARDS)is one of the serious diseases in the neonatal period,which seriously harms the health of newborns.The main treatment methods include ventilator-assisted ventilation,PS replacement,anti-infection and nutritional support,etc.The alternative treatment of PS is one of the unique treatment methods of nARDS,and the use of PS can significantly improve hypoxemia and respiratory distress in neonates.This paper reviewed the types,dosage,administration route,administration time,and repeated administration of PS in the treatment of nARDS.

关 键 词：肺表面活性物质 急性呼吸窘迫综合征 新生儿 

分 类 号：R722.105[医药卫生—儿科]