Mirror-like tongue is an important predictor of acute heart failure:a cohort study of acute heart failure in Chinese patients  

作　　者：CHEN Yunhu YIN Moqing FAN Lihua JIANG Xuechun ZHANG Tao ZHU Xingyu XU Hongfeng 

机构地区：[1]Department of Cardiology,Taicang TCM Hospital Affiliated to Nanjing University of Chinese Medicine,Suzhou 215400,China [2]Department of Cardiology,Changzhou Hospital affiliated with Nanjing University of Chinese Medicine,Changzhou 213003,China [3]Department of Clinical Pharmacy,Taicang TCM Hospital Affiliated to Nanjing University of Chinese Medicine,Suzhou 215400,China

出　　处：《Journal of Traditional Chinese Medicine》2023年第6期1243-1251,共9页中医杂志（英文版）

基　　金：the 2019 Suzhou Science and Technology Development Plan (the Fourth Batch of Basic Research on People’s Livelihood,Science and Technology,and Medical and Health Applications):Applied Research on Diuretic Resistance of Zhuling Decoction (No.SYSD2019201)

摘　　要：OBJECTIVE:To reveal that mirror-like tongue,observed via a noninvasive inspection,is a powerful indicator of the severity and prognosis of patients with acute heart failure(AHF).METHODS:This was an observational,prospective study.A total of 408 patients who met the inclusion criteria and were diagnosed with AHF for the first time at Taicang Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine from August 2019 to January 2021 were selected as the research subjects.According to their tongue fur,the patients were divided into group A(mirror-like tongue group)and group B(non-mirror-like tongue group).The clinical characteristics and incidence of major adverse cardiovascular events(MACEs)within 1 year of follow-up were systematically compared between the two groups.RESULTS:Sixty-five patients were included in group A,and 343 patients were included in group B.There were 32 males and 33 females in group A and 168 males and 175 females in group B.The average age of the overall population was 64 years old,and the average age of group A was significantly higher than that of group B(74 vs 62 years,P<0.001).Compared with that in group B,the left ventricular ejection fraction(LVEF)in group A was significantly lower(35%vs 42%,P<0.001),and the log N-terminal pro B-type natriuretic peptide(NT-proBNP)level was significantly higher(4.0 vs 3.4,P<0.001).The proportion of the combined application of vasoactive drugs in group A was significantly higher than that in group B(64%vs 38%,P<0.001).Group B had a higher proportion of coronary angiography(29.5%vs 16.9%,P=0.038).Group A was more inclined to require mechanical ventilation than group B(33.9%vs 22.5%,P=0.049).The length of hospital stay in group A was significantly longer than that in group B(13.1 vs 7.6,P<0.001).The incidence of MACEs,such as recurrence of AHF,new myocardial infarction and stroke,in group A within one year was higher than that in group B(P=0.007,0.009,<0.001).The incidence of cumulative MACEs in group A was significantly high

关 键 词：heart failure risk factors FUR Yin deficiency cohort studies 

分 类 号：R541.6[医药卫生—心血管疾病]