窄谱中波紫外线联合其他方法治疗白癜风的研究进展  

Narrow-band ultraviolet B phototherapy combined with other therapies for the treatment of vitiligo

作　　者：曾蕊 徐秀莲 Zeng Rui;Xu Xiulian(Hospital of Dermatology,Chinese Academy of Medical Sciences and Peking Union Medical College,Nanjing 210042,China)

机构地区：[1]中国医学科学院,北京协和医学院皮肤病医院病理科,南京210042

出　　处：《中华皮肤科杂志》2024年第1期75-78,共4页Chinese Journal of Dermatology

摘　　要：窄谱中波紫外线(NB-UVB)是治疗泛发型白癜风的一线方案,但单一治疗效果有限,疗程长.NB-UVB联合其他治疗能缩短疗程,提高疗效,是目前临床上常用的治疗模式.本文就NB-UVB联合其他方法如糖皮质激素、阿法诺肽、钙调磷酸酶抑制剂、JAK抑制剂、富血小板血浆、CO_(2)点阵激光、外科手术治疗白癜风的研究进展进行综述,旨在为临床提供更多治疗选择.Narrow-band ultraviolet B(NB-UVB)phototherapy has been regarded as the first-line treatment of generalized vitiligo.However,NB-UVB monotherapy exhibits limited efficacy with a long course of treatment.NB-UVB phototherapy combined with other therapies can shorten the course of treatment and improve the therapeutic effect,and has become a commonly used therapeutic regimen in clinical practice.This review summarizes research progress in the combined therapies of NB-UVB with other approaches for the treatment of vitiligo,such as glucocorticoids,afamelanotide,calcineurin inhibitors,Janus kinase inhibitors,platelet-rich plasma,fractional CO_(2) laser and surgical treatment,in order to provide more options for clinical treatment of vitiligo.

关 键 词：白癜风 紫外线疗法 窄谱中波紫外线 联合治疗 

分 类 号：R758.41[医药卫生—皮肤病学与性病学]