贵州省2022年学校肺结核接触者筛查结果分析  

Analysis of the results of school tuberculosis contacts screening,Guizhou,2022

作　　者：廖龙 陈慧娟 李进岚[2] 王芸[1] 何昱颖[2] 陈璞 杨婕[2] 黄爱菊[2] 荀梦君[2] 安露 LIAO Long;CHEN Hui-juan;LI Jin-lan;WANG Yun;HE Yu-ying;CHEN Pu;YANG Jie;HUANG Ai-ju;XUN Meng-jun;AN lu(School of Public Health,the Key Laboratory of Environmental Pollution Monitoring and Disease Control,Ministry of Education,Guizhou Medical University,Guiyang,Guizhou 561113,China;不详)

机构地区：[1]贵州医科大学公共卫生与健康学院,环境污染与疾病监控教育部重点实验室,贵州贵阳561113 [2]贵州省疾病预防控制中心结核病防治研究所

出　　处：《现代预防医学》2023年第24期4463-4468,共6页Modern Preventive Medicine

基　　金：贵州省科技厅项目(黔科合支撑[2021]一般030)。

摘　　要：目的分析贵州省学校肺结核接触者潜伏感染及检出病例情况,探究潜伏感染和发病的危险因素,为贵州省采取针对性学校结核病防控措施提供参考。方法通过贵州省疾控云平台———学校结核病管理系统收集2022年贵州省内学校肺结核病例接触者筛查资料,共纳入1165例肺结核指示病例、110079名肺结核接触者作为研究对象,采用多因素logistic回归模型分析潜伏感染、检出病例的相关影响因素。结果2022年贵州省接受筛查的肺结核接触者潜伏感染率为11.00%、病例检出率为0.12%。年龄≥15岁学生组(13.24%)的潜伏感染率高于<15岁学生组(7.16%),差异有统计学意义(χ^(2)=965.966,P<0.001);毕节市潜伏感染率(10.44%)和病例检出率(0.17%)均较高;潜伏感染学生预防性服药率为26.73%;检出病例中27.21%的患者TST检测为阴性;寄宿学生(OR=1.28,95%CI:1.21~1.35)、密切接触者(OR=1.57,95%CI:1.47~1.68)潜伏感染的风险较高;年龄≥15岁是接触学生潜伏感染和发病的共同危险因素。结论应继续加强学校结核病防控工作,加强毕节市等地区的密切接触学生的监测和随访,广泛开展肺结核健康宣教,持续提高结核潜伏感染学生接受预防性服药的积极性。Objective To analysis the situation of latent infection and detected cases of tuberculosis among tuberculosis contacts in school of Guizhou Province,to explore the risk factors of latent infection and detected cases of tuberculosis,and to provide references for adopting targeted tuberculosis prevention and control measures in schools of Guizhou Province.Methods Data on screening of contacts of school tuberculosis cases in Guizhou Province in 2022 were collected through the Guizhou Provincial CDC Cloud Platform-School Tuberculosis Management System.A total of 1165 cases of indicative cases of tuberculosis and 110079 tuberculosis contacts were included as study subjects for the analysis,and the multifactorial logistic regression model was used to analyze the influencing factors related to the latent infections and detected cases.Results The latent infection rate of tuberculosis contacts screened in Guizhou Province in 2022 was 11.00%,and the case detection rate was 0.12%.The latent infection rate of students the aged≥15 years(13.24%)was higher than that of the aged<15 years(7.16%),with statistically significant differences(χ^(2)=965.966,P<0.001).The latent infection rate(10.44%)and the case detection(0.17%)were higher in Bijie City.The rate of prophylactic medication administration among latently infected students was 26.73%.The TST test of 27.21%of the case was negative.The boarding students(OR=1.28,95%CI:1.21-1.35),and close contacts(OR=1.57,95%CI:1.47-1.68)were at higher risk of latent infection,and age≥15 years was a common risk factor for latent infection and morbidity in contact students.Conclusion It is necessary to continue to strengthen tuberculosis prevention and control in schools,enhance monitoring and follow-up of students in close contact in Bijie City and other areas,conduct extensive tuberculosis health education,and to improve the willingness of students with latent tuberculosis infection to receive preventive medication continuously.

关 键 词：肺结核 学生 密切接触者 筛查 

分 类 号：R521[医药卫生—内科学]