肝硬化失代偿期病人衰弱及肌少症干预管理最佳循证证据总结  

Summary of the best evidence-based evidence for the intervention and management of asthenia and sarcopenia in patients with decompensation period of cirrhosis

作　　者：曾芳[1] 高莹[1] 方笑珍 林瑞弟 王凤智 陶星彤 黄霞 ZENG Fang;GAO Ying;FANG Xiaozhen;LIN Ruidi;WANG Fengzhi;TAO Xingtong;HUANG Xia(Houjie Hospital of Dongguan,Guangdong 523945 China)

机构地区：[1]东莞市厚街医院,523945

出　　处：《全科护理》2024年第2期214-220,共7页Chinese General Practice Nursing

基　　金：2023年东莞市社会发展科技重点项目,编号:20231800936172。

摘　　要：目的:检索、评级和汇总肝硬化失代偿期病人衰弱及肌少症干预及管理的最佳证据,为临床干预管理提供参考依据。方法:检索the Cochrane Library、CINAHL、Best Practice、Up To Date、NICE、Embase、PubMed、Web of Science、欧洲肝脏疾病研究会、谷歌学术、万方数据库、中国知网、医脉通等,获取肝硬化失代偿期病人衰弱及肌少症干预管理所有的证据。结果:共纳入9篇文献,其中指南6篇、专家共识2篇、系统评价1篇,共计汇总27条最佳证据。主要涉及肝硬化失代偿期病人衰弱及肌少症的概念识别、衰弱及肌少症的最佳评估工具选择、衰弱及肌少症营养干预管理、运动干预管理、药物干预管理、肝硬化失代偿期病人衰弱及肌少症整体化的干预理念7个方面。结论:肝硬化失代偿期病人衰弱及肌少症干预管理的最佳证据丰富,但是部分数据来源于国外的循证资源,应用时仍需进行本土化。Objective:To search,rate and summarize the best evidence for the intervention and management of enervation and sarcopenia in patients with decompensation period of cirrhosis,so as to provide reference for clinical intervention and management.Methods:The database were searched including Cochrane Library,CINAHL,Best Practice,Up To Date,NICE,Embase,PubMed,Web of Science,European Association of Liver Diseases,Google Academic,Wanfang Database,CNKI,Yimaitong,then to obtain all the evidence for the intervention and management of enervation and sarcopenia in patients with decompensation period of cirrhosis.Results:A total of 9 papers were included,including 6 guidelines,2 expert consensus and 1 systematic review.A total of 27 pieces of best evidence were summarized.It mainly involves 7 aspects:concept recognition of enervation and sarcopenia in patients with decompensation period of cirrhosis,selection of the best assessment tool for enervation and sarcopenia,nutritional intervention management for enervation and sarcopenia,exercise intervention management,drug intervention management,and integrated intervention concept for enervation and sarcopenia in patients with decompensation period of cirrhosis.Conclusions:The best evidence for the intervention and management of enervation and sarcopenia in patients with decompensation period of cirrhosis is abundant,but some of the data are from foreign evidence-based resources,and they need to be localized when used.

关 键 词：肝硬化失代偿期 衰弱 肌少症 循证护理 

分 类 号：R473.5[医药卫生—护理学]