海南省特发性性早熟女童中医证型分布特点研究  

Study on the Distribution Characteristics of Traditional Chinese MedicineSyndrome Types in Girls with Idiopathic Central PrecociousPuberty from Hainan Province

作　　者：王铭 许文婷 黄靖涵 WANG Ming;XU Wen-Ting;HUANG Jing-Han(Hainan Women and Children’s Medical Center,Haikou 571103 Hainan,China)

机构地区：[1]海南省妇女儿童医学中心,海南海口571103

出　　处：《广州中医药大学学报》2024年第1期27-32,共6页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：海南省卫生健康行业科研项目(编号:21A200421)。

摘　　要：【目的】探讨海南省特发性性早熟(idiopathic central precocious puberty,ICPP)女童的中医证型分布特点。【方法】回顾性选取海南省妇女儿童医学中心于2019年1月至2021年12月收治的216例ICPP女童为研究对象,对其中医证候进行频数统计和分级评分,并按阴虚火旺证、气血亏虚证和心肾不交证三大中医证型,探讨其中医证型分布特点。【结果】(1)发病年龄方面,216例ICPP女童的发病年龄在4~10岁之间,平均发病年龄为(7.15±1.06)岁,其中满7岁且不满8岁阶段的ICPP女童发病率最高,为49.54%。(2)中医证型方面,三大证型中,阴虚火旺证的占比最高(147例,占68.06%),其次是气血亏虚证(41例,占18.98%)及心肾不交证(28例,占12.96%)。(3)中医证候方面,临床常见证候(频率>25.0%)按出现频率由高到低依次为:怕热盗汗、手足心热、乳房胀痛、性情急躁、脉细数、大便干结、咽干口燥、潮热、多食肥甘、舌红少苔、抑郁、精神乏力、颧红、失眠多梦、舌红苔黄和口苦口干等16种。(4)各证型的年龄分布方面:阴虚火旺证和气血亏虚证均多见于满7岁且不满8岁年龄段的ICPP女童(占58.50%和51.22%),心肾不交证多见于满8岁且不满9岁年龄段的ICPP女童(占89.29%)。【结论】阴虚火旺证是海南省ICPP女童占比最高的中医证型。研究性早熟女童的中医证型分布,有助于性早熟女童的早期临床症状观察以及疾病的早期诊断,从而为ICPP女童的临床辨证用药提供线索和依据。Objective To investigate the distribution characteristics of traditional Chinese medicine(TCM)syndromes in girls with idiopathic central precocious puberty(ICPP)from Hainan province.Methods A total of 216 cases of ICPP girls admitted to Hainan Women and Children’s Medical Centre from January 2019 to December 2021 were retrospectively collected.The frequency statistics and grading of TCM syndromes in the included ICPP girls were carried out,and the distribution characteristics of TCM syndromes were discussed on the basis of the analysis of the three TCM syndrome types of yin deficiency and fire exuberance syndrome,qi and blood insufficiency syndrome and incoordination between heart and kidney syndrome.Results(1)The age of ICPP onset in 216 girls were between 4 and 10 years old,with an average onset age of(7.15±1.06)years.The highest incidence rate of ICPP was found in the girls aged over 7 years old while less than 8 years old,which was 49.54%.(2)Of the three TCM syndrome types,yin deficiency and fire exuberance syndrome accounted for the highest proportion(147 cases,68.06%),followed by the qi and blood insufficiency syndrome(41 cases,18.98%)and the incoordination between heart and kidney syndrome(28 cases,12.96%).(3)The common 16 TCM symptoms(frequency>25.0%)in descending order of frequency were aversion to heat and night sweating,feverish sensation in soles and palms,breast distension and pain,irritability,thready and rapid pulse,dry stools,dry throat and mouth, hot flushes, excessive intake of fat and sweet food, red tongue with less fur, depression, mentalweakness,flushed cheeks,insomnia and dreaminess,red tongue with yellow fur,and bitterness and dryness inthe mouth.(4)The distribution of the age in ICPP girls with various syndromes was as follows:yin deficiency andfire exuberance syndrome and qi and blood insufficiency syndrome were more common in the ICPP girls aged over 7years old while less than 8 years old(accounting for 58.50% and 51.22%),and incoordination between heart andkidney syndrome was more c

关 键 词：海南省 特发性性早熟 女童 中医证型 阴虚火旺 气血亏虚 心肾不交 

分 类 号：R272.6[医药卫生—中医儿科学]