非糖尿病患者肠外营养期间血糖控制及胰岛素应用的现状与进展  

Status and progress of glycemic control and insulin application during parenteral nutrition in non-diabetic patients

作　　者：周玉洁 兰宁 张琳 范珊琳 汪品秀 袁文臻[6] Zhou Yujie;Lan Ning;Zhang Lin;Fan Shanlin;Wang Pinxiu;Yuan Wenzhen(Department of Medical Oncology,Gansu Provincial Central Hospital,Lanzhou 730050,China;Department of Radiotherapy,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China;Center for Family Medicine and Integrative Health Care,Beijing United Family Hospital,Beijing 100015,China;Department of Oncology,Taikang Xianlin Drum Tower Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing 210023,China;Department of Oncology,Shucheng People's Hospital,Lu'an 231300,Anhui,China;Department of Surgical Oncology,The First Hospital of Lanzhou University,Lanzhou 730000,China)

机构地区：[1]甘肃省中心医院肿瘤内科,甘肃兰州730050 [2]西安交通大学第一附属医院肿瘤放疗科,陕西西安710061 [3]北京和睦家医院全科医疗中心,北京100015 [4]南京大学医学院附属泰康仙林鼓楼医院肿瘤科,江苏南京210023 [5]安徽省舒城县人民医院肿瘤科,安徽六安231300 [6]兰州大学第一医院肿瘤外科,甘肃兰州730000

出　　处：《兰州大学学报（医学版）》2023年第11期79-87,共9页Journal of Lanzhou University（Medical Sciences）

基　　金：甘肃省卫生行业科研计划资助项目(GSWSKY2022-19)。

摘　　要：高血糖(HG)是住院患者肠外营养(PN)期间常见的并发症,与高感染率等并发症和死亡风险相关,通常需要胰岛素治疗。目前国际上对于非糖尿病(NDM)患者PN时是否常规应用胰岛素预防HG、使用胰岛素的最佳途径及剂量、方案存在诸多争议。本研究通过检索相关文献并总结提出NDM患者PN时胰岛素应用的优化策略。Hyperglycemia(HG)is a common complication of parenteral nutrition(PN)in hospitalized patients associated with increased rates of complications such as infection and mortality.Treatment requires insulin therapy.At present,there are many disputes about whether to routinely use insulin to prevent HG and what is the best way and dosage scheme of using insulin in non-diabetic(NDM)patients during PN.By searching and summarizing the relevant literature,we put forward the optimization strategy of PN insulin application in NDM patients.

关 键 词：肠外营养 非糖尿病 高血糖 胰岛素 

分 类 号：R1[医药卫生—公共卫生与预防医学] R459.3