人造子宫技术在早产动物体外生命支持中的研究进展  

Research progress in artificial uterus technology via premature animal experiments

作　　者：胡洋洋 张莉 Hu Yangyang;Zhang Li(School of Clinical Medicine,Xi'an Medical University,Xi'an 710000,Shaanxi,China;Department of Neonatology,Northwest Women's and Children's Hospital,Xi'an 710061,Shaanxi,China)

机构地区：[1]西安医学院临床医学院,陕西西安710000 [2]西北妇女儿童医院新生儿科,陕西西安710061

出　　处：《兰州大学学报（医学版）》2023年第11期88-94,共7页Journal of Lanzhou University（Medical Sciences）

基　　金：中国医药教育协会2022重点课题资助项目(2022KTZ018);西安市科技局2022科研资助项目(22YXYJ0101)。

摘　　要：介绍了人造子宫作为模拟子宫内环境的体外生命支持装置,可帮助超早产儿维持正常的生长发育和器官成熟,避免不必要的医疗干预,减少并发症的发生。本文围绕体外氧合器、回路系统、无菌环境、营养供应及医疗管理等多方面,综述了人造子宫技术从早产动物试验向人类超早产儿临床转化的可能性,并强调需要克服的挑战和技术难题。该技术有望成为显著改善超早产儿的临床预后的重要创新途径。This article introduced the artificial uterus as an extracorporeal life support device simulating the intrauterine environment,aiming to assist the normal growth and organ maturation of extremely premature infants,avoiding unnecessary medical interventions and reducing the occurrence of complications.The paper focused on various aspects,including extracorporeal oxygenators,circuit systems,aseptic environments,nutrition supply and medical management,providing an overview of the potential transition of artificial uterus technology from early animal experiments to clinical application.Also emphasized were the challenges and technical difficulties needing to be overcome.Looking ahead,this technology is expected to become a significant innovative approach in improving the clinical prognosis of extremely premature infants.

关 键 词：人造子宫 超早产儿 早产动物 体外生命支持 体外氧合器 体外回路装置 肺发育 

分 类 号：R541[医药卫生—心血管疾病]