尿流动力学检查参数及前列腺特异性抗原水平与老年良性前列腺增生患者发生急性尿潴留的相关性研究  

Study on the correlation between urodynamic examination parameters and prostate specific antigen level of acute urinary retention in elderly patients with benign prostatic hyperplasia

作　　者：陈垒 吴嵩 曲直 CHEN Lei;WU Song;QU Zhi(Department of Urology,Pinggu District Hospital,Beijing 101200,China)

机构地区：[1]北京市平谷区医院泌尿外科,北京101200

出　　处：《中国性科学》2024年第1期16-20,共5页Chinese Journal of Human Sexuality

摘　　要：目的分析尿流动力学检查参数及前列腺特异性抗原(PSA)水平与老年良性前列腺增生(BPH)患者发生急性尿潴留(AUR)的相关性。方法选取2021年1月至2023年1月北京市平谷区医院收治的100例BPH患者作为研究对象。根据患者是否出现AUR分为AUR组和非AUR组,每组50例。检测两组的膀胱顺应性、尿流率、膀胱初始尿意容量、最大逼尿肌压力、膀胱残余尿量、最大膀胱容量;检测两组血清总PSA(tPSA)和游离PSA(fPSA)水平。结果AUR组尿流率、最大逼尿肌压力均显著低于非AUR组,差异具有统计学意义(P<0.05);AUR组膀胱初始尿意容量、最大膀胱容量、膀胱顺应性、膀胱残余尿量均显著高于非AUR组,差异具有统计学意义(P<0.05);AUR组血清tPSA及fPSA水平均显著高于非AUR组,差异具有统计学意义(P<0.05)。尿流率、最大逼尿肌压力与BPH患者发生AUR呈显著负相关关系(P<0.05);膀胱初始尿意容量、最大膀胱容量、膀胱顺应性、膀胱残余尿量、tPSA及fPSA与BPH患者发生AUR呈显著正相关关系(P<0.05);低尿流率、低最大逼尿肌压力、高膀胱初始尿意容量、高最大膀胱容量、高膀胱顺应性、高膀胱残余尿量、高tPSA及高fPSA是影响BPH患者发生AUR的独立危险因素(P<0.05)。结论尿流动力学检查参数及PSA与老年BPH患者发生AUR具有相关性,临床可通过监测尿流动力学检查参数及PSA水平分析老年BPH患者发生AUR的潜在风险。Objective To analyze the relationship between urodynamic examination parameters and prostate specific antigen level of acute urinary retention(AUR)in elderly benign prostatic hyperplasia(BPH)patients.Methods A total of 100 patients with BPH admitted to Pinggu District Hospital from January 2021 to January 2023 were selected as the study subjects.The patients were divided into AUR group and non-AUR group according to whether they had AUR,with 50 cases in each group.The bladder compliance,urine flow rate,initial bladder capacity,maximum detrusor pressure,bladder residual urine volume,and maximum bladder capacity,serum total PSA(tPSA)and free PSA(fPSA)levels in the the two groups were measured.Results The urine flow rate and maximal detrusor pressure in the AUR group were significantly lower than those in the non-AUR group,and the differences were statistically significant(P<0.05).The initial bladder capacity,maximum bladder capacity,bladder compliance and bladder residual urine volume in the AUR group were significantly higher than those in the non-AUR group,and the differences were statistically significant(P<0.05).Serum tPSA and fPSA levels in the AUR group were significantly higher than those in the nonAUR group,and the difference was statistically significant(P<0.05).Urine flow rate,maximal detrusor pressure were negatively correlated with the AUR of BPH(P<0.05).The initial bladder capacity,maximum bladder capacity,bladder compliance,bladder residual urine volume,tPSA and fPSA were significantly positively correlated with the AUR of BPH(P<0.05).Low urine flow rate,low maximum detrusor pressure,high initial bladder capacity,high maximum bladder capacity,high bladder compliance,high bladder residual urine volume,high tPSA,and high fPSA were the independent risk factors for AUR of BPH(P<0.05).Conclusions Urodynamic parameters and PSA are correlated with the occurrence of AUR in elderly BPH patients,and the potential risk of AUR in elderly BPH patients can be analyzed by monitoring urodynamic examination parameters

关 键 词：尿流动力学检查参数 前列腺特异性抗原 老年 良性前列腺增生 急性尿潴留 

分 类 号：R697[医药卫生—泌尿科学]