人工流产术中艾司氯胺酮复合丙泊酚麻醉效果及对女性焦虑抑郁影响  

Effect of esketamine combined with propofol for anesthesia during induced abortion and its influence on the anxiety and depression of the women

作　　者：李军仕 王卫萍 李迪 晋冰韦 LI Junshi;WANG Weiping;LI Di;JIN Bingwei(The First Affiliated Hospital of Zhengzhou University,Henan Province International Joint Laboratory of Pain,Cognition and Emotion,Zhengzhou,Henan Province,450000)

机构地区：[1]郑州大学第一附属医院,河南省疼痛认知与情绪研究国际联合实验室,450000

出　　处：《中国计划生育学杂志》2024年第1期29-32,38,共5页Chinese Journal of Family Planning

摘　　要：目的:探讨艾司氯胺酮复合丙泊酚麻醉用于无痛人工流产术的麻醉效果及对女性术后焦虑抑郁的影响.方法:选取2022年8月-2023年6月本院收治的拟行无痛人工流产术女性80例,随机数字表法分为观察组与对照组各40例,分别应用艾司氯胺酮联合丙泊酚及舒芬太尼联合丙泊酚麻醉方案,观察和对比两组丙泊酚使用量、诱导时间、苏醒时间、留观时间及疼痛(VAS)评分,并在术前、术后1周应用焦虑(SAS)和抑郁(SDS)量表评估受术者心理状况,评估心理韧性及恢复质量.结果:两组丙泊酚使用量、诱导时间、苏醒时间、留观时间及VAS评分均无差异(P>0.05);术后1周,两组SAS、SDS评分均下降,且观察组(45.08±8.76分、44.93±8.26分)低于对照组(52.01±7.99分、50.15±6.71分);两组心理韧性评分及恢复质量评分均提高,且观察组高于对照组(均P<0.05).结论:艾司氯胺酮复合丙泊酚麻醉方案应用于无痛人工流产术,在满足麻醉效果前提下,能够缓解受术者术后焦虑抑郁等不良情绪,提高生活质量,可作为临床优化麻醉方案的可行性选择.Objective:To investigate the effect of cskctaminc combined with propofol for anesthesia during painless abortion of women,and to study its influence on the anxiety and depression of the women.Methods:80 pregnant women who wanted painless abortion were selected and were divided into two groups(40 cases in each group)according to the random number table from August 2022 to June 2023.The women in the observation group were given cskctaminc combined with propofol for anesthesia during abortion,and the women in the control group were given sufentanil combined with propofol for anesthesia during abortion.The dosage of propofol used,the induction time of anesthesia,the awakening time,the conservative time in hospital and the VAS score of the women were observed and were compared between the two groups.The anxicty(SAS)and dcprcssion(SDS)scales were used to measure the psychological status and resilience before abortion and in 1 week after abortion,and the quality of recovery of the women.Results:There were no significant differences in the dosage of propofol used,the induction time of anesthesia,the awakening time,the conservative time in hospital and the VAS score of the women between the two groups(P>0.05).In 1 week after abortion,the SAS and SDS scores of the women in the two groups had decreased significantly,and which(45.08±8.76 points and 44.93±8.26 points)of the women in the observation group were significantly lower than thosc(52.01±7.99 points and 50.15±6.71 points)of the women in the control group.The psychological resilience and recovery quality score of the women in the two groups had increased significantly,and which of the women in the observation group were significantly higher than those of the women in the control group(all P<0.05).Conclusion:Esketamine combined with propofol uses for anesthesia during abortion of the women,which can relieve the postoperative adverse emotions,such as anxiety and depression,and can improeve the quality of life of the women under the premise of satisfying the anestheti

关 键 词：无痛人工流产术 艾司氯胺酮 丙泊酚 焦虑 抑郁 心理 生活质量 

分 类 号：R614[医药卫生—麻醉学]