血尿安胶囊联合左氧氟沙星治疗女性尿路感染疗效及对患者炎症因子影响  

Effect of Xueniaoan capsule combined with levofloxacin for treating female patients with urinary tract infection and its influence on the inflammatory factors

作　　者：杨薛枫 聂湘黔 冯明杨 胡建新 YANG Xuefeng;NIE Xiangqian;FENG Mingyang;HU Jianxin(School of Clinical Medicine,Guizhou Medical University,Guiyang,Guizhou Province,550004;Guizhou Province People's Hospital)

机构地区：[1]贵州医科大学临床医学院,贵阳550004 [2]贵州省人民医院

出　　处：《中国计划生育学杂志》2024年第1期44-47,52,共5页Chinese Journal of Family Planning

摘　　要：目的:探究女性尿路感染(UTI)患者应用血尿安胶囊联合左氧氟沙星治疗效果及对炎症因子及不良反应影响.方法:选取2020年6月-2023年2月本院妇科收治的160例UTI患者,随机数字表法分成观察组、对照组各80例,两组均给予左氧氟沙星治疗,观察组加以血尿安胶囊治疗,治疗2个月.观察用药后两组临床疗效、尿液指标、炎症水平、阴道PH值以及不良反应.结果:治疗后,观察组临床疗效(92.5%)高于对照组(81.3%),两组尿白细胞数与尿细菌数均下降且观察组(3.44±1.02个/HP、665.45±122.53个/μl)低于对照组(7.67±2.11个/HP、934.61±158.35个/μl),两组用药后C-反应蛋白、高迁移率族蛋白B1及降钙素原水平均下降且观察组(12.32±5.45mg/L、60.04±12.44ng/ml、0.54±0.12ng/ml)低于对照组(20.32±8.78mg/L、82.63±15.51ng/ml、2.13±0.43ng/ml),两组阴道PH值均下降且用药后观察组(4.54±0.77)低于对照组(5.23±0.85),不良反应总发生率观察组(7.5%)低于对照组(18.8%)(均P<0.05).结论:血尿安胶囊联合左氧氟沙星可提高UTI临床疗效,有效减轻患者炎症,降低阴道PH值和用药不良反应.Objective:To explore the effect of Xueniaoan capsule combined with levofloxacin for treating female patients with urinary tract infcction(UTI),and to study its influence on the inflammatory level and the adverse reactions of the patients.Methods:A total of 160 female patients with UTI were selected and divided into observation group(n=80)and control group(n=80.)according to the random number table method from June 2020 to February 2023.The patients in the control group were treated with levofloxacin,and the patients in the observation group were treated with Xueniaoan capsule combined with levofloxacin.The clinical efficacy,the urine index,the inflammation level,the vaginal PH value and the incidence of adverse reactions of the patients in the two groups were observed.Results:The clinical cfficacy(92.5%)of the patients in the observation group was significantly higher than that(81.3%)of the patients in the control group."The urine white blood cells counts and the urine bacteria level of the patients in the two groups after treatment had decreased significantly,and which(3.44±1.02 pieces/HP and 665.45±122.53/μl)of the patients in the observation group were significantly lower than thosc(7.67±2.11/HP and 93-4.61±158.35/μl)of the patients in the control group.The levels of C reaction protein,high mobility group protein B1 and calcitonin of the patients in two groups after treatment had decreased significantly,and which(12.32±5.45 mg/L,60.04±12.44 mg/ml and 0.54±0.12 mg/ml)of the patients in the observation group were significantly lower than thosc(20.32±8.78 mm mg/L,82.63±15.51 mg/ml and 2.13±0.43 mg/ml)of the patients in the control group.The vaginal PH value of the patients after treatment had decreased significantly,and which(4.54±0.77)of the patients in the observation group was significantly lower than that(5.23±0.85)of the patients in the control group.The total incidence of adverse rcactions(7.5%)of the patients in the observation group was significantly lower than that(18.8%)of the patients in

关 键 词：女性尿路感染 血尿安胶囊 左氧氟沙星 临床疗效 炎症因子 尿液指标 不良反应 

分 类 号：R691.3[医药卫生—泌尿科学]