用药教育对雾化吸入治疗儿童喘息性疾病疗效和安全性的影响研究  

Study on the effect of medication education on the efficacy and safety of aerosol inhalation in the treatment of asthmatic diseases in children

作　　者：张怡 李美月 刘俊 ZHANG Yi;LI Mei-yue;LIU Jun(Dongguan Kanghua Hospital,Dongguan 523080,China)

机构地区：[1]东莞康华医院,523080

出　　处：《中国实用医药》2024年第1期135-139,共5页China Practical Medicine

基　　金：2021年东莞市社会发展科技面上项目(项目编号:20211800902872)。

摘　　要：目的观察用药教育对雾化吸入治疗儿童喘息性疾病患儿临床治疗效果和安全性的影响。方法186例儿童喘息性疾病患儿,随机分为对照组与观察组,各93例。两组患儿均给予综合对症治疗,对照组不单独给予指导,观察组给予用药教育。比较两组患儿咳嗽症状改善效果、夜间睡眠恢复效果、依从性、家长满意度、用药不良反应发生率、临床症状消失时间、肺功能指标。结果观察组患儿咳嗽症状改善总有效率97.85%高于对照组的90.32%(P<0.05)。观察组患儿夜间睡眠恢复总有效率98.92%高于对照组的92.47%(P<0.05)。观察组患儿依从率94.62%高于对照组的86.02%(P<0.05)。观察组患儿家长总满意度98.92%高于对照组的92.47%(P<0.05)。观察组患儿用药不良反应发生率6.45%低于对照组的16.13%(P<0.05)。观察组患儿咳嗽、肺部湿啰音、喘憋、肺部哮鸣音消失时间分别为(6.01±0.45)、(4.07±0.34)、(4.32±0.45)、(4.34±0.24)d,短于对照组的(6.58±0.56)、(4.62±0.44)、(5.22±0.51)、(4.97±0.36)d(P<0.05)。治疗后,观察组患儿第1秒用力呼气容积(FEV1)(1.94±0.22)L、呼气峰值流速(PEF)(2.74±0.23)L/s、第1秒用力呼气容积与用力肺活量的比值(FEV1/FVC)(60.44±2.55)%高于对照组的(1.73±0.23)L、(2.56±0.21)L/s、(55.52±3.65)%(P<0.05)。结论在儿童喘息性疾病患儿接受雾化吸入治疗中实施用药教育措施,患儿的咳嗽症状得到了明显的缓解,睡眠质量提升,并可减轻患儿在雾化给药后出现的不适,缩短了患儿临床症状消失时间,肺功能明显改善,获得患儿家属的认可。Objective To observe the effect of medication education on the efficacy and safety of aerosol inhalation in the treatment of asthmatic diseases in children.Methods 186 children with asthmatic disease were randomly divided into a control group and an observation group,with 93 cases in each group.The control group was not given separate guidance,and the observation group was given medication education.Both groups were compared in terms of improvement effect of cough symptom,night sleep recovery,compliance,parental satisfaction,incidence of adverse drug reactions,disappearance time of clinical symptoms and pulmonary function indexes.Results The total effective rate of improvement of cough symptom in the observation group(97.85%)was higher than the control group(90.32%)(P<0.05).The total effective rate of night sleep recovery of 98.92%in the observation group was higher than that of 92.47%in the control group(P<0.05).The compliance rate of 94.62%in the observation group was higher than that of 86.02%in the control group(P<0.05).The total satisfaction of parents of 98.92%in the observation group was higher than that of 92.47%in the control group(P<0.05).The incidence of adverse drug reactions of 6.45%in the observation group was lower than that of 16.13%in the control group(P<0.05).The disappearance time of cough,lung moist rale,asthma and lung wheezing sound in the observation group was(6.01±0.45),(4.07±0.34),(4.32±0.45)and(4.34±0.24)d,which was shorter than those of(6.58±0.56),(4.62±0.44),(5.22±0.51)and(4.97±0.36)d in the control group(P<0.05).After treatment,the forced expiratory volume in one second(FEV1),peak expiratory flow rate(PEF),FEV1/FVC were(1.94±0.22)L,(2.74±0.23)L/s,(60.44±2.55)%in the observation group,which were higher than those of(1.73±0.23)L,(2.56±0.21)L/s,(55.52±3.65)%in the control group(P<0.05).Conclusion In the implementation of medication education measures in the treatment of asthmatic diseases in children receiving aerosol inhalation,the cough symptoms of the children have been

关 键 词：儿童 喘息性疾病 雾化吸入 用药教育 咳嗽症状 夜间睡眠 满意度 

分 类 号：R725.6[医药卫生—儿科]