门冬氨酸钾镁联合胺碘酮治疗急性心肌梗死室性心律失常的效果  

Therapeutic Effects of Potassium Magnesium Menthylate Combined with Amiodarone in Treating Ventricular Arrhyth⁃mia in Acute Myocardial Infarction

作　　者：石少虎 Shi Shaohu(Department of Cardiovascular Medicine,Xintai People's Hospital,Xintai 271200,Shandong Province,China)

机构地区：[1]新泰市人民医院心血管内科,山东新泰271200

出　　处：《中外医药研究》2023年第25期39-41,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:探究急性心肌梗死室性心律失常应用门冬氨酸钾镁与胺碘酮治疗的临床疗效。方法:选取2021年6月—2022年6月新泰市人民医院收治的急性心肌梗死室性心律失常患者76例,采用随机数字表法分为两组,各38例。对照组应用胺碘酮治疗,研究组应用门冬氨酸钾镁与胺碘酮联合治疗。对比两组患者临床疗效,心功能指标[左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVEDS)、左室射血分数(LVEF)],炎性因子水平[白细胞介素-6(IL-6)、肿瘤坏死因子α(TNF-α)],转复律时间,住院时间,不良反应。结果:研究组患者治疗后总有效率高于对照组,差异有统计学意义(P<0.05)。研究组患者治疗后,LVEDD、LVEDS水平低于对照组,LVEF水平高于对照组,差异有统计学意义(P<0.05)。研究组患者治疗后IL-6、TNF-α水平低于对照组,差异有统计学意义(P<0.05)。研究组转复律时间、平均住院时间均较对照组更短,差异有统计学意义(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论:门冬氨酸钾镁联合胺碘酮治疗急性心肌梗死室性心律失常,效果良好,临床应用价值高。Objective:To investigate the clinical efficacy of acute myocardial infarction ventricular arrhythmia treated with potassium magnesium menthylate and amiodarone.Methods:76 patients with acute myocardial infarction ventricular arrhythmia admitted to the People's Hospital of Xintai City from June 2021 to June 2022 were selected and divided into two groups of 38 cases each by using the method of randomized numerical table.The control group was treated with amiodarone,and the study group was treated with the combination of potassium magnesium menthylate and amiodarone.The two groups were compared in the following terms:the therapeutic efficacy,cardiac function indexes including left ventricular end-diastolic internal diameter(LVEDD),left ventricular end-systolic internal diameter(LVEDS)and left ventricular ejection fraction(LVEF),inflammatory indexes such as interleukin-6(IL-6)and tumor necrosis factor alpha(TNF-α),time to regain rhythm,hospital stay length,and adverse reactions.Results:The total effective rate of patients in the study group after treatment was higher than the control group,and the difference was statistically significant(P<0.05).After the treatment of the patients in the study group,the levels of LVEDD and LVEDS were lower than those of the control group,and the level of LVEF was higher than that of the control group,and the difference was statistically significant(P<0.05).The levels of IL-6 and TNF-αin the study group were lower than those in the control group after treatment,and the difference was statistically significant(P<0.05).The time to return to normal rhythm and the average hospitalization length were shorter in the study group than in the control group,and the difference was statistically significant(P<0.05).Comparing the incidence of adverse reactions between the two groups did not show a statistically significant difference(P>0.05).Conclusion:Potassium magnesium menthonate combined with amiodarone in the treatment of ventricular arrhythmia in acute myocardial infarction is effective an

关 键 词：门冬氨酸钾镁 胺碘酮 急性心肌梗死 室性心律失常 

分 类 号：R54[医药卫生—心血管疾病]