早期高压氧联合标准大骨瓣开颅术治疗重型颅脑外伤的临床效果  

Clinical Effect of Early Hyperbaric Oxygen Combined with Standard Large Bone Flap Craniotomy in the Treatment of Severe Craniocerebral Injury

作　　者：陈汝行 Chen Ruxing(Department of Craniocerebral Surgery,Guangzhou Hospital of Integrated Traditional Chinese and Western Medicine,Guangzhou 510800,Guangdong Province,China)

机构地区：[1]广州市中西医结合医院颅脑外科,广东广州510800

出　　处：《中外医药研究》2023年第25期57-59,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:探讨早期高压氧联合标准大骨瓣开颅术治疗重型颅脑外伤的临床效果。方法:选取2022年4月—2023年4月广州市中西医结合医院收治的重型颅脑外伤患者58例,按照随机数字表法分为两组,各29例。对照组采用标准大骨瓣开颅术治疗,研究组采用早期高压氧联合标准大骨瓣开颅术治疗。比较两组患者治疗后临床效果。结果:研究组患者治疗后总有效率高于对照组,差异有统计学意义(P<0.05)。研究组患者治疗后7 d、14 d、21 d格拉斯哥昏迷(GCS)评分高于对照组,差异有统计学意义(P<0.05)。研究组患者治疗后神经功能缺损情况评分低于对照组,日常生活能力评分高于对照组,差异有统计学意义(P<0.05)。研究组患者治疗后并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论:早期高压氧联合标准大骨瓣开颅术治疗重型颅脑外伤的临床疗效显著,可有效改善患者的临床症状,降低并发症发生率和神经功能造成的损伤,提高GCS评分和日常生活能力,值得推广。Objective:To investigate the clinical effect of early hyperbaric oxygen combined with standard large bone flap craniotomy in the treatment of severe craniocerebral injury.Methods:Fifty-eight patients with severe craniocerebral trauma admitted to Guangzhou Hospital of Integrated Traditional Chinese and Western Medicine from April 2022 to April 2023 were selected and divided into two groups according to random number table method,with twenty-nine cases in each group.The control group was treated with standard large bone flap craniotomy,and the study group was treated with early hyperbaric oxygen combined with standard large bone flap craniotomy.The clinical effect after treatment was compared between the two groups.Results:The total effective rate of the study group was higher than the control group,and the difference was statistically significant(P<0.05);The Glasgow coma(GCS)score of the study group was higher than that of the control group at 7,14 and 21 days after treatment,and the difference was statistically significant(P<0.05);After treatment,the score of neurological impairment in the study group was lower than that in the control group,and the score of daily living ability was higher than that in the control group,with statistical significance(P<0.05);The incidence of complications in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Early hyperbaric oxygen combined with standard large bone craniotomy for the treatment of severe craniocerebral trauma has significant clinical efficacy,which can effectively improve the clinical symptoms of patients,reduce the incidence of complications and neurological damage,and improve the GCS score and daily living ability,which is worthy of promotion.

关 键 词：重型颅脑外伤 早期高压氧 标准大骨瓣开颅术 

分 类 号：R65[医药卫生—外科学]