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作 者:季如如 吕洪海 朱冬梅 Ji Ruru;Lyv Honghai;Zhu Dongmei(Department of Pediatric Surgery,the Second Affiliated Hospital of Nantong University,Nantong 226001,Jiangsu Province,China)
机构地区:[1]南通大学第二附属医院小儿外科,江苏南通226001
出 处:《中外医药研究》2023年第26期75-77,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
摘 要:目的:探究传统手术及腹腔镜手术对小儿急性阑尾炎穿孔的临床效果。方法:选取2020年1月—2022年10月南通大学第二附属医院收治的小儿急性阑尾炎穿孔患儿400例为研究对象,随机排序后按奇偶数分为对照组与试验组,各200例。对照组采取传统手术,试验组行腹腔镜手术。比较两组患儿手术指标、并发症及血清炎性指标。结果:试验组患儿手术时间、术中出血量、排气时间、下床活动时间、肠道恢复时间及住院时间均优于对照组,差异有统计学意义(P<0.001);试验组患儿并发症发生率低于对照组,差异有统计学意义(P<0.001);治疗后,两组患儿白细胞介素-6、白细胞介素-8、肿瘤坏死因子α水平均降低,试验组低于对照组,差异有统计学意义(P<0.05)。结论:腹腔镜手术治疗小儿急性阑尾炎穿孔,可降低手术出血量,缩短手术时间、排气时间、下床活动时间及住院时间,降低术后并发症发生率,改善血清炎性指标。Objective:To investigate the clinical effects of traditional surgery and laparoscopic surgery on pediatric acute appen⁃dicitis perforation.Methods:Four hundred children with pediatric acute appendicitis perforation admitted to the Second Affiliat⁃ed Hospital of Nantong University from January 2020 to October 2022 were selected as the study subjects,and were randomly sorted and divided into the control group and the experimental group according to the number of odd-even,with two hundred cases in each group.In the control group,traditional surgery was performed,and in the experimental group,laparoscopic sur⁃gery was performed.Surgical indexes,complications and serum inflammatory indexes were compared between the two groups.Results:The operation time,intraoperative bleeding,exhaust time,time to get out of bed,intestinal recovery time and hospital⁃ization time of the children in the experimental group were better than those in the control group,and the difference was statis⁃tically significant(P<0.001);The complication rate of children in the experimental group was lower than that of the control group,and the difference was statistically significant(P<0.001);After treatment,the levels of interleukin-6,interleukin-8 and tumor necrosis factorαwere reduced in both groups,and the experimental group was lower than the control group,with a statis⁃tically significant difference(P<0.05).Conclusion:Laparoscopic surgery for the treatment of pediatric acute appendicitis perfora⁃tion can reduce the amount of surgical bleeding,shorten the duration of surgery,time of exhaustion,time of getting out of bed and hospitalization,reduce the incidence of postoperative complications,and improve the serum inflammatory index.
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