中医药多元证据整合方法学MERGE框架  

Multi-evidence Integration Methodology for Traditional Chinese Medicine:the MERGE Framework

作　　者：赖鸿皓 王浙 李滢 唐文静 王蓓蓓 孙培栋 孙铭谣 黄嘉杰 肖志攀 李颖 赵晨 商洪才[7] 杨克虎[8,9,10] 刘杰 葛龙[1,2,9,10] LAI Honghao;WANG Zhe;LI Ying;TANG Wenjing;WANG Beibei;SUN Peidong;SUN Mingyao;HUANG Jiajie;XIAO Zhipan;LI Ying;ZHAO Chen;SHANG Hongcai;YANG Kehu;LIU Jie;GE Long(Evidence-based Social Science Research Center,School of Public Health,School of Basic Medical Sciences,Lanzhou University,Lanzhou 730000,China;Department of Social Science and Health Management,School of Public Health,School of Basic Medical Sciences,Lanzhou University,Lanzhou 730000,China;Evidence-based Nursing Center,School of Nursing,School of Basic Medical Sciences,Lanzhou University,Lanzhou 730000,China;College of Nursing,Gansu University of Chinese Medicine,Lanzhou 730030,China;School of Traditional Chinese and Western Medicine,Gansu University of Chinese Medicine,Lanzhou 730030,China;Institute of Basic Research In Clinical Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China;Key Laboratory of Chinese Internal Medicine of Ministry of Education,Beijing Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;Evidence-based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Lanzhou 730000,China;Collaborative Innovation Center for Evidence-based Traditional Chinese Medicine in Gansu Province,Lanzhou 730000,China;Key Laboratory of Evidence-based Medicine and Knowledge Translation of Gansu Province,Lanzhou 730000,China;Department of Oncology,Guanganmen Hospital,Chinese Academy of Traditional Chinese Medicine,Beijing 100053,China;China Center for Evidence-based Traditional Chinese Medicine,Beijing 100700,China)

机构地区：[1]兰州大学公共卫生学院循证社会科学研究中心,兰州730000 [2]兰州大学公共卫生学院社会医学与卫生事业管理研究所,兰州730000 [3]兰州大学护理学院循证护理研究中心,兰州730000 [4]甘肃中医药大学护理学院,兰州730030 [5]甘肃中医药大学中西医结合学院,兰州730030 [6]中国中医科学院中医临床基础医学研究所,北京100700 [7]北京中医药大学东直门医院中医内科学教育部和北京市重点实验室,北京100700 [8]兰州大学基础医学院循证医学中心,兰州730000 [9]甘肃省循证中医药协同创新基地,兰州730000 [10]甘肃省循证医学与临床转化重点实验室,兰州730000 [11]中国中医科学院广安门医院肿瘤科,北京100053 [12]中国中医药循证医学中心,北京100700

出　　处：《协和医学杂志》2024年第1期172-182,共11页Medical Journal of Peking Union Medical College Hospital

基　　金：国家自然科学基金(82204931);中国中医科学院科技创新工程(CI2021A05502)。

摘　　要：在循证医学时代下,依托规范的技术方法和标准化的操作规程发掘中医药独特优势,是实现中医药现代化、国际化发展并惠泽人类的必由之路。中医理论、人用经验和研究证据三结合证据体系的提出标志着中医药特色评价体系思维方法取得了重要进步,经过恰当方法整合后的多元证据体是中医药临床指南推荐意见和循证卫生决策的有力支撑。本文基于当前国际证据合成与分级方法学前沿进展,初步提出中医药多元证据整合的方法学框架——MERGE(Merge Evidence-based Research and artificial intelliGence to support smart dEcision)框架,以期为中医药循证医学方法学体系的完善和发展提供借鉴和参考。In the era of evidence-based medicine,it is necessary to explore the unique advantages of traditional Chinese medicine(TCM)based on standardized technical methods and operating procedures in order to achieve the modernization and internationalization of TCM and benefit all humanity.The proposal of a three-pronged evidence system combining TCM theory,human experience and experimental evidence marks an important progress in the thinking method of the TCM evaluation system.The multi-evidence body integrated through appropriate methods provides a strong support for the clinical guideline recommendations and evidence-based health decision-making in TCM.Based on the current methodological progress of international evidence synthesis and grading,this paper proposes a novel approach for integrating multi-evidence in TCM:the MERGE framework.The aim is to establish a solid foundation for the development of this methodology and provide guidance for the advancement of evidence-based medicine framework in TCM.

关 键 词：循证医学 中医药 多元证据 证据整合 MERGE框架 

分 类 号：R181.2[医药卫生—流行病学] R21[医药卫生—公共卫生与预防医学]