弹性髓内钉固定技术联合经皮穿刺人工骨注射治疗单纯性骨囊肿的应用研究  

Application Study of Elastic Intramedullary Nail Fixation Technology Combined with Percutaneous Puncture and Artificial Bone Injection in the Treatment of Simple Bone Cysts

作　　者：王俊东[1] 贺小张 王桃[1] 钟锋 彭生凌 WANG Jundong;HE Xiaozhang;WANG Tao;ZHONG Feng;PENG Shengling(Deparement of Pediatric,Pingxiang People's Hospital,Pingxiang 337000,China;不详)

机构地区：[1]萍乡市人民医院儿外科,江西萍乡337000

出　　处：《中国医学创新》2024年第2期15-20,共6页Medical Innovation of China

基　　金：江西省卫生健康委科技计划项目(SKJP420201001)。

摘　　要：目的:探究弹性髓内钉固定技术联合经皮穿刺人工骨注射治疗单纯性骨囊肿的效果。方法:纳入萍乡市人民医院儿外科于2015年7月—2020年7月经病理学检查确诊的64例单纯性骨囊肿患儿作为研究对象。采用随机数字表法将患儿分为联合组与对照组,其中对照组采用经皮穿刺人工骨注射+外固定+甲泼尼龙琥珀酸钠治疗,在此基础上联合组加弹性髓内钉固定技术治疗。所有患儿均需给予6个月连续随访。比较两组临床疗效、肌肉骨骼肿瘤协会(MSTS)评分、炎症因子[白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]、手术时间、术中出血量、住院时间;记录两组住院期间不良反应发生情况。结果:研究期间,联合组因未完成随访脱落1例,因改用其他治疗方案脱落1例,对照组因未完成后续随访脱落2例。联合组30例,对照组30例。联合组临床总有效率明显高于对照组,差异有统计学意义(P<0.05);术后1、3个月,两组MSTS评分较术前均增高,且联合组MSTS评分均高于对照组,差异均有统计学意义(P<0.05)。术后第7天,联合组的IL-6、TNF-α均明显低于对照组,差异均有统计学意义(P<0.05)。两组术中出血量比较,差异无统计学意义(P>0.05)。联合组住院时间明显短于对照组,手术时间明显长于对照组,差异均有统计学意义(P<0.05)。两组患儿均未出现不良反应。结论:弹性髓内钉固定技术联合经皮穿刺人工骨注射治疗可改善单纯性骨囊肿患儿肢体功能、降低炎症因子水平、缩短住院时间。Objective:To investigate the effect of elastic intramedullary nail fixation technology combined with percutaneous puncture and artificial bone injection in the treatment of simple bone cysts.Method:A total of 64 children with simple bone cyst diagnosed by pathology examination from July 2015 to July 2020 in the Department of Pediatric of Pingxiang People's Hospital were included as the research objects.The children were divided into the combined group and the control group by random number table method.The control group was treated with percutaneous puncture artificial bone injection+external fixation+Methylprednisolone Sodium Succinate,and on this basis,the combined group was treated with elastic intramedullary nail fixation technology.All children should be followed up for 6 months.The clinical efficacy,musculoskeletal tumor society(MSTS)scores,inflammatory factors[interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)],surgical time,intraoperative bleeding volume,and length of hospital stay between two groups were compared;the occurrence of adverse reactions during hospitalization in two groups were recorded.Result:During the study period,one case was lost in the combined group due to incomplete follow-up,one case was lost due to switching to other treatment plans,and two cases were lost in the control group due to incomplete follow-up.30 cases in the combination group and 30 cases in the control group.The clinical total effective rate of the combined group was significantly higher than that of the control group,the difference was statistically significant(P<0.05).At 1 month and 3 months after surgery,the MSTS scores of both groups increased compared to those before surgery,and the MSTS scores of the combined group were higher than those of the control group,the differences were statistically significant(P<0.05).On the 7th day after surgery IL-6 and TNF-αin the combined group were significantly lower than those in the control group,the differences were statistically significant(P<0.05).There was no statisticall

关 键 词：单纯性骨囊肿 弹性髓内钉 经皮穿刺人工骨注射 

分 类 号：R726.8[医药卫生—儿科]