基于抑制MnO_(2)纳米片刻蚀金纳米棒的尿酸比色测定  

Colorimetric Detection of Uric Acid Based on Inhibition of MnO_(2)Nanosheets Etching of Gold Nanorods

作　　者：黄叶颖 唐嫚瑾 陆怡凡 谭正森 文辉忠[1] 王益林[1] Huang Yeying;Tang Manjin;Lu Yifan;Tan Zhengsen;Wen Huizhong;Wang Yilin(School of Chemistry and Chemical Engineering,Guangxi University,Nanning 530004,China)

机构地区：[1]广西大学化学化工学院,广西南宁530004

出　　处：《山东化工》2023年第24期116-118,123,共4页Shandong Chemical Industry

基　　金：广西大学大学生创新创业训练计划项目(S202210593285);广西高等教育本科教学改革工程项目(2021JGB118)。

摘　　要：制备了MnO_(2)纳米片(MnO_(2)NSs)和金纳米棒(Au NRs)。Au NRs被MnO_(2)NSs刻蚀导致其纵向表面等离子体共振(LSPR)吸收蓝移,而尿酸(UA)对Au NRs的刻蚀具有抑制作用,基于此原理,建立了一种以波长变化为响应信号的比色分析法用于UA的高灵敏测定。考察了pH值、孵育时间和MnO_(2)NSs浓度等因素对信号响应的影响。在选定的实验条件下,当UA浓度在1.5~70μmol/L范围内时,波长移动值与浓度呈良好的线性关系,方法的检出限为0.72μmol/L,应用于实际样品中UA含量的测定,结果满意。MnO_(2)nanosheets(MnO_(2)NSs)and gold nanorods(Au NRs)were prepared.Au NRs are etched by MnO_(2)NSs,resulting in a longitudinal surface plasmon resonance(LSPR)absorption blue shift,while uric acid(UA)has an inhibitory effect on the etching of Au NRs.Based on these,a colorimetric analysis method with wavelength change as the response signal was established for the highly sensitive determination of UA.The effects of pH value,incubation time,and MnO_(2)NSs concentration on signal response were investigated.Under the selected experimental conditions,there is a good linear relationship between wavelength shift value and UA concentration in the range of 1.5 to 70μmol/L with a detection limit of 0.72μmol/L.The method has been used for the detection of UA content in practical samples with satisfactory results.

关 键 词：纳米片 纳米棒 尿酸 比色 

分 类 号：O657.3[理学—分析化学]