肌少-骨质疏松症的研究进展  

Research progress on osteosarcopenia

作　　者：李悦芃 董娟[1] 张任飞[1] 陈璐 邱蕾[1] Li Yuepeng;Dong Juan;Zhang Renfei;Chen Lu;Qiu Lei(Department of Health Care,Beijing Hospital,National Center of Gerontology Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]北京医院保健医疗部、国家老年医学研究中心、中国医学科学院老年医学研究院,北京100730

出　　处：《中华老年医学杂志》2024年第1期77-81,共5页Chinese Journal of Geriatrics

摘　　要：肌少—骨质疏松症是一种肌少症和骨质疏松症并存的老年综合征。发病机制涉及遗传基因、骨骼-肌肉机械作用、内分泌调节机制、分子信号通路等多种因素。在临床实践中,除了需综合评估危险因素外,还需筛查骨密度、肌肉力量、肌肉质量及机体整体功能情况。干预措施主要包括运动疗法、营养支持和药物等。Osteosarcopenia is a geriatric syndrome referring to the co-existence of osteoporosis and sarcopenia.Its pathogenesis involves factors such as genetics,mechanics of the musculoskeletal system,endocrine regulatory mechanisms and molecular signaling pathways.In clinical practice,aside from comprehensive assessment of risk factors,screening of bone density,muscle strength,muscle mass and the overall body function must also be undertaken.Intervention measures primarily include therapeutic exercise,nutritional support and drugs.

关 键 词：骨质疏松 肌骨骼疾病 治疗 

分 类 号：R685[医药卫生—骨科学] R580[医药卫生—外科学]