重症新型冠状病毒感染合并侵袭性肺曲霉病和肺毛霉病诊治专家共识  

Expert consensus on diagnosis and treatment of severe CovID-19 associated pulmonary aspergillosisandmucormycosis

作　　者：中国医师协会呼吸医师分会危重症学组 中华医学会呼吸病学分会 詹庆元[2] 苏欣 黄琳娜[4] 贺航咏[5] 蔡莹[4] 陈玥 郭翎茜 刘智博[4] 王诗尧 吴小静[4] 郭建[6] 孙禾 孙文逹 Critical Care Medicine Group of Chinese Association of Chest Physicians;Chinese Thoracic Society;Zhan Qingyuan;Su Xin(Critical Care Medicine Group of Chinese Association of Chest Physicians,Chinese Thoracic Society Corresponding author:Zhan Qingyuan,Department of Pulmonary and Critical Care Medicine,China-Japan Friendship Hospital,National Center for Respiratory Medicine,National Clinical Research Center for Respiratory Diseases,Institute of Respiratory Medicine,Chinese Academy of Medical Sciences,Beijing 100029,China,Email:[e-mail];Department of Pulmonary and Critical Care Medicine,China-Japan Friendship Hospital,National Center for Respiratory Medicine,National Clinical Research Center for Respiratory Diseases,Institute of Respiratory Medicine,Chinese Academy of Medical Sciences,Beijing 100029,China;Department of Respiratory and Critical Care Medicine,Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School,Nanjing 210008,China)

机构地区：[1]不详 [2]中日友好医院呼吸与危重症医学科,北京100029 [3]南京大学医学院附属鼓楼医院呼吸与危重症医学科,南京210008 [4]中日友好医院 [5]首都医科大学附属北京朝阳医院 [6]同济大学附属东方医院 [7]南京医科大学第一附属医院

出　　处：《中华结核和呼吸杂志》2024年第1期10-23,共14页Chinese Journal of Tuberculosis and Respiratory Diseases

基　　金：中央高水平医院临床科研项目(2022-NHLHCRF-LX-01-01);中国医学科学院医学与健康科技创新工程项目(2022-I2M-JB-016)。

摘　　要：重症COVID-19相关肺曲霉病(CAPA)的发病率及病死率均较高。而新型冠状病毒感染相关肺毛霉病(CAPM)虽然相对少见,但疾病本身的严重性加之误诊及诊断延误也导致其病死率居高不下。目前,重症CAPA及CAPM的诊断及治疗均面临巨大挑战。如何早期诊断并规范治疗是救治成功的关键。因此,中国医师协会呼吸医师分会危重症学组与中华医学会呼吸病学分会危重症学组发起并组织相关领域专家,基于目前的循证医学证据及临床实践经验,撰写本共识,以期提高重症CAPA及CAPM患者的临床救治。工作组结合文献及临床实践经验,形成共识的初步文本。经两次讨论会,最终确定16条核心推荐意见并给出推荐强度,分为推荐、建议及不推荐。critically ll patients.Although COVID-19 associated mucormycosis(CAPM)is relatively rare,its severity and often a delayed diagnosis or misdiagnosis lead to its high mortality.The diagnosis and treatment of CAPA and CAPM in critically ill patients are challenging.Early diagnosis and a standardized therapy are the two most important factors for a good outcome.Therefore,a working group of experts from Chinese Thoracic Society and Chinese Association of Chest Physicians Critical Care Group was organized to develop this consensus based on the current medical evidence and clinical practice,in order to improve the ability of clinical treatment for critically ill patients with CAPA and CAPM.The working group drafted a preliminary text based on the literature and clinical practice experience.Following two rounds of discussion,16 final recommendations were made,with the recommendation strength divided into recommend,suggest and not recommend.

关 键 词：中国医师协会 中华医学会 循证医学证据 肺曲霉病 临床救治 规范治疗 推荐意见 冠状病毒感染 

分 类 号：R511[医药卫生—内科学] R519[医药卫生—临床医学]