脑深部电刺激治疗帕金森病定位方式的研究进展  

Research progress on localization method of deep brain stimulation for Parkinson's disease

作　　者：汪玉棋 郐国虎 蒋伟 WANG Yu-qi;KUAI Guo-hu;JIANG Wei(Department of Neurosurgery,Tianyou Hospital,Clinical College of Wuhan University of Science and Technology,Wuhan Hubei 430064,China;Graduate School,Wuhan University of Science and Technology,Wuhan Hubei 430064,China;Department of Neurosurgery,Tongji Hospital,Huazhong University of Science and Technology,Wuhan Hubei 430030,China)

机构地区：[1]武汉科技大学临床学院附属天佑医院神经外科,湖北武汉430064 [2]武汉科技大学研究生院,湖北武汉430064 [3]华中科技大学附属同济医院神经外科,湖北武汉430030

出　　处：《局解手术学杂志》2024年第2期183-186,共4页Journal of Regional Anatomy and Operative Surgery

基　　金：湖北省自然科学基金(ZRMS2020000484)。

摘　　要：自1947年以来,帕金森病(PD)的治疗迎来了微创手术时代,脑深部电刺激(DBS)治疗晚期PD逐渐被认可和应用。随着科学技术水平的不断提高与进步,临床医师对DBS核团定位精准度的要求越来越高。DBS核团定位方式主要包括解剖层面和生理层面,分别对应影像学定位方式和微电极信号定位方式。近80年间,DBS的精准度不断提高,已成为治疗晚期PD的有效方法。本文就DBS定位的发展及定位操作的原理进行综述。Since 1947,the treatment of Parkinson's disease(PD)has ushered in the era of minimally invasive surgery,and deep brain stimulation(DBS)has been gradually recognized and applied for the treatment of advanced PD.With the continuous improvement and progress of science and technology,clinicians have higher and higher requirements on the accuracy of DBS nuclei positioning.The localization methods of DBS nuclei mainly include anatomical and physiological aspects,corresponding to imaging localization methods and microelectrode signal localization methods respectively.In recent 80 years,the accuracy of DBS has been continuously improved,and it has become an effective method for the treatment of advanced PD.This paper summarizes the development of DBS positioning and the principle of positioning operation.

关 键 词：帕金森病 脑深部电刺激 定位方式 

分 类 号：R615[医药卫生—外科学]