多囊卵巢综合征继发不孕肾虚血瘀证应用补肾活血化瘀汤的临床效果分析  

Clinical Effect Analysis of Application of Bushen Huoxue Huayu Decoction in Polycystic Ovary Syndrome Secondary Infertility with Kidney Defi⁃ciency and Blood Stasis Certificate

作　　者：刘代军 于婷 凌霞[1] 徐岚 LIU Daijun;YU Ting;LING Xia;XU Lan(Gynecology and Obstetrics Diagnosis and Treatment Center,Affiliated Hospital of Changchun University of Traditional Chinese Medicine,Changchun,Jilin Province,130021 China;Department of Malternal Health Care,Erdao District Changqing Community Health Service Center,Changchun,Jilin Province,130033 China)

机构地区：[1]长春中医药大学附属医院妇产诊疗中心,吉林长春130021 [2]长春市二道区长青社区卫生服务中心妇保科,吉林长春130033

出　　处：《中外医疗》2023年第34期27-30,共4页China & Foreign Medical Treatment

摘　　要：目的 探讨多囊卵巢综合征继发不孕肾虚血瘀证应用补肾活血化瘀汤的临床效果。方法 选取2022年1月—2023年6月在长春中医药大学附属医院治疗的90例多囊卵巢综合征继发不孕肾虚血瘀证患者为研究对象,根据随机数表法分为对照组和观察组,对照组45例采用枸橼酸氯米芬片治疗,观察组45例采用补肾活血化瘀汤治疗。分析治疗前后组间及组内的卵巢储备功能指标以及卵巢动脉的血流指标的变化,并观察不良反应。结果 治疗后两组的窦卵泡数量减少,卵巢体积减小,与治疗前对比,差异有统计学意义(P<0.05);治疗后观察组的窦卵泡数量少于对照组,卵巢体积小于对照组,差异有统计学意义(P<0.05)。治疗后两组的卵巢动脉的收缩期峰值血流速度(peak systolic velocity, PSV)降低,阻力指数(resistance index, RI)、搏动指数(pulsatility index, PI)增加,与治疗前对比,差异有统计学意义(P<0.05);治疗后观察组的PSV低于对照组,RI、PI高于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率为2.22%,低于对照组的28.88%,差异有统计学意义(χ^(2)=12.180,P<0.05)。结论 在中医辨证为肾虚血瘀证的多囊卵巢综合征继发不孕患者的治疗当中,应用补肾活血化瘀汤能够增强卵巢的储备功能,改善卵巢血流状态。Objective To investigate the clinical effect of the application of Bushen Huoxue Huayu decoction in poly-cystic ovary syndrome secondary infertility with kidney deficiency and blood stasis certificate.Methods A total of 90 patients with secondary infertility of pdycystic ovary syndrome with kidney deficiency and blood stasis syndrome treated in the Affiliated Hospital of Changchun University of Trditional Chinese Medicine from January 2022 to June 2023 were selected as the study objects.They were divided into control group and observation group according to ran-dom number table method.45 cases in the control group were treated with Clomiphene citrate tablets,and 45 cases in the observation group were treated with Bushen Huoxue Huayu Decoction.The changes of ovarian reserve function in-dex and ovarian artery blood flow index were analyzed before and after treatment,and the adverse reactions were ob-served.Results After treatment,the number of sinus follicles and ovarian volume decreased in the two groups,com-pared with before treatment,the differences were statistically significant(P<0.05).After treatment,the number of si-nus follicles and ovarian volume in the observation group were lower than those in the control group,and the differ-ences were statistically significant(P<0.05).After treatment,the peak systolic velocity(PSV)of the ovarian arteries of the two groups decreased,and the resistance index(RI)and pulsatility index(PI)increased.Compared with those be-fore treatment,the differences were statistically significant(P<0.05).After treatment,PSV of observation group was lower than control group,RI and PI were higher than those in the control group,and the differences were statistically significant that in the(P<0.05).The incidence of adverse reactions in the observation group was 2.22%,lower than that in the control group(28.88%),and the difference was statistically significant(χ^(2)=12.180,P<0.05).Conclusion Among the treatments for patients with polycystic ovary syndrome secondary infertility who were diagn

关 键 词：多囊卵巢综合征 继发不孕 肾虚血瘀证 补肾活血化瘀汤 窦卵泡数量 卵巢体积 卵巢动脉血流 

分 类 号：R271.14[医药卫生—中医妇科学]