应用早期与延期手术治疗新生儿坏死性小肠结肠炎的疗效评价  

Evaluation of the Effect of Early and Delayed Operation on Neonatal Nec⁃rotizing Enterocolitis

作　　者：杨怡 黄圣余 谢承 YANG Yi;HUANG Shengyu;XIE Cheng(Department of General Surgery,Fuzhou First General Hospital Children's Specialized Hospital Area(Fujian Fuzhou Children's Hospital),Fuzhou,Fujian Province,350000 China)

机构地区：[1]福州市第一总医院儿童专科院区(福建省福州儿童医院)普通外科,福建福州350000

出　　处：《中外医疗》2023年第34期43-46,共4页China & Foreign Medical Treatment

摘　　要：目的 探讨早期与延期手术治疗新生儿坏死性小肠结肠炎的疗效。方法 方便选取2020年3月—2023年3月福州市第一总医院儿童专科院区收治的85例新生儿坏死性小肠结肠炎患儿为研究对象,按照治疗方案不同将其划分为参照组、研究组。研究组17例行早期手术治疗。参照组68例采取延期手术治疗方案。比较两组患儿的短期预后、并发症发生率、术后6个月随访结果。结果 研究组治愈率为100.00%,比参照组的79.41%高,研究组病情恶化至Ⅲ期及病死率为0低于参照组的20.59%,差异有统计学意义(χ^(2)=4.190、4.190,P<0.05)。研究组感染性休克、肠穿孔、败血症、腹膜炎等并发症发生率为0低于参照组的20.59%,差异有统计学意义(P<0.05)。术后6个月,研究组体质量比参照组高,远期并发症(排便异常、不完全肠梗阻)发生率为0低于参照组的20.59%,差异有统计学意义(P<0.05)。结论 早期手术治疗新生儿坏死性小肠结肠炎的近期与远期疗效均更为显著,能够降低坏死性小肠结肠炎患儿并发症的发生率,还可提高其治愈率。同时,此种治疗形式对提高患儿的远期预后价值显著,有助于增加其体质量,提高其生活质量。Objective To investigate the effect of early and delayed operation on neonatal necrotizing enterocolitis.Methods 85 children with neonatal necrotizing enterocolitis admitted to the Children's Specialized Hospital of Fuzhou First General Hospital from March 2020 to March 2023 were conveniently selected as the study objects,and divided into reference group and study group according to different treatment plans.In the study group,17 patients received early surgical treatment.In the reference group,68 cases were treated with delayed operationt.The short-term progno-sis,complication rate and follow-up results at 6 months after operation were compared between the two groups.Re-sults The cure rate of the study group was 100.00%,which was higher than that of the reference group(79.41%),and the proportion of disease progression to stageⅢand mortality rate in the study group was 0,which was lower than that of the reference group(20.59%),and the difference was statistically significant(χ^(2)=4.190,4.190,P<0.05).The inci-dence of complications such as septic shock,intestinal perforation,sepsis and peritonitis in the study group was 0 lower than that in the reference group(20.59%),and the difference was statistically significant(P<0.05).6 months af-ter surgery,the body mass of the study group was higher than that of the reference group,and the incidence of long-term complications(abnormal bowel movement and incomplete intestinal obstruction)was 0,lower than that of the ref-erence group(20.59%),and the difference was statistically significant(P<0.05).Conclusion Early surgical treatment of neonatal necrotizing enterocolitis has more significant short-term and long-term effects,which can reduce the inci-dence of complications in children with necrotizing enterocolitis and increase the cure rate.At the same time,this form of treatment has significant value in improving the long-term prognosis of children,helping to increase their body mass and improve their quality of life.

关 键 词：新生儿坏死性小肠结肠炎 手术治疗 手术时机 早期 延期手术 并发症 

分 类 号：R5[医药卫生—内科学]