农业实验动物资源的培育及应用  

Breeding and applications of agricultural laboratory animal resources

作　　者：高彩霞[1] 张贺 于海波[1] 孟庆文[1] 李昌文[1] 陈洪岩[1] 夏长友[1] GAO CaiXia;ZHANG He;YU HaiBo;MENG QingWen;LI ChangWen;CHEN HongYan;XIA ChangYou(State Key Laboratory for Animal Disease Control and Prevention,Heilongjiang Provincial Key Laboratory of Laboratory Animal and Comparative Medicine,National Poultry Laboratory Animal Resource Center,Harbin Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Harbin150069,China)

机构地区：[1]中国农业科学院哈尔滨兽医研究所,动物疫病防控全国重点实验室,黑龙江省实验动物与比较医学重点实验室,国家禽类实验动物资源库,哈尔滨150069

出　　处：《中国科学：生命科学》2023年第12期1794-1805,共12页Scientia Sinica(Vitae)

基　　金：国家重点研发计划(批准号:2021YFF0703000,2021YFF0703100,2022YFF0710500,2022YFF0711200);国家生猪技术创新中心先导科技项目(批准号:NCTIP-XD1C09);黑龙江省重点研发计划(批准号:GZ20210010);中央级公益性科研院所基本科研业务费专项(批准号:1610302020008,1610302022018)资助。

摘　　要：农业实验动物是指来源于农业养殖的动物或宠物,按照相关标准经过严格培育成的实验动物,主要包括:鸡、鸭、猪、马、牛、羊、犬、貂等.农业实验动物是国家科技创新的基础性、战略性生物资源和支撑生命科学研究的重要条件之一,更是畜禽疫病防控技术研究的核心依靠.因此,本文综述了国内外农业实验动物的发展概况、国内农业实验动物平台的建设及资源培育情况,分析了农业实验动物在畜禽疫病防控研究、生物制品研发、生产和检验研究、临床教学、人类医学模型创制及医用材料评价中的应用.Agricultural laboratory animals refer to animals or pets from agricultural breeding that have undergone strict selections and standardized breeding,mainly including chickens,ducks,pigs,horses,cattle,sheep,dogs,and minks.They are the basic and strategic biological resources for science and technological innovation and an important support to life science research.Moreover,the technology research on animal disease prevention and control heavily depend on agricultural laboratory animals.Therefore,we reviewed the development of agricultural laboratory animals at home and abroad,the platform construction of domestic agricultural laboratory animals,and the breeding of resources.We also analyzed the applications of agricultural laboratory animals in the prevention and control of animal diseases,research and development of biological products,production and testing,clinical teaching,creation of human medical models,and evaluation of medical materials.

关 键 词：农业实验动物 资源 培育 应用 

分 类 号：Q95-33[生物学—动物学]