精液支原体阳性对体外受精周期胚胎发育情况的影响  

Impact of Mycoplasma genitalium positive semen on the development of embryos in in vitro fertilization cycles

作　　者：翁崇双 王淑林 张长平 Weng Chongshuang;Wang Shulin;Zhang Changping(Shangrao Maternal and Child Health Hospital,Shangrao,Jiangxi 334000,China)

机构地区：[1]上饶市妇幼保健院生殖科,江西上饶334000

出　　处：《实用医技杂志》2023年第12期867-871,共5页Journal of Practical Medical Techniques

摘　　要：目的探讨男性精液支原体阳性对于接受体外受精-胚胎移植(IVF-ET)者受精周期胚胎发育情况影响。方法选择2022年9月至2023年9月接受IVF-ET的男性不育者100例为研究对象,采集研究对象的精液,进行精液支原体的培养和检测,根据检测结果分成阳性组与阴性组。均进行IVF-ET治疗,收集患者的一般资料以及精液测定情况,随访妊娠情况以及胚胎发育情况。结果100例男性患者,检测精液支原体阳性24例(24%);阳性组精子密度为(46±5)×10^(6)个/ml、精子总数为(116±15)×10^(6)个/射精、前向运动(PR)为(42±5)%、精子正常形态率为(2.4±0.6)%,均低于阴性组,差异具有统计学意义(t=10.199,11.387,6.578,4.953,P均<0.01)。阳性组优质胚胎率为(25±4)%、移植胚胎数为(1.7±0.4),均低于阴性组,差异有统计学意义(t=12.000,3.208,P均<0.05)。结论男性不育行IVF-ET的患者,精液支原体阳性对IVF-ET妊娠结局不会造成明显影响,但是精液支原体阳性会降低优质胚胎率,减少移植胚胎数。Objective To investigate the effect of Mycoplasma hyopneumoniae positivity of male semen on the development of embryos in fertilizationcycles of in vitro fertilization-embryo transfer(IVF-ET)recipients.Methods A total of 100 infertile men who received IVF-ET from September 2022 to September 2023 were selected as the research objects,and their semen was collected and cultured and detected by mycoplasma in semen.According to the detection results,they were divided into positive group and negative group.All patients were treated with IVF-ET,and their general data and semen determination were collected,and their pregnancy and embryo development were followed up.Results Of the 100 male patients,24(24.00%)were positive for mycoplasma in semen.In the positive group,the sperm density was(46±5)×10^(6)ml,the total number of sperm was(116±15)×10^(6)/ejaculation,the forward movement(PR)was(42±5)%,and the normal sperm morphology rate was(2.4±0.6)%,all of which were lower than those of the negative group,and the differences were statistically significant(t=10.199,11.387,6.578,4.953,all P<0.01).The rate of high-quality embryos in the positive group was(25±4)%,and the number of transferred embryos was(1.70.4),both of which were lower than those in the negative group,with statistical significance(t=12.000,3.208,P<0.05).Conclusion Male infertility patients undergoing IVF-ET have no obvious influence on the pregnancy outcome of IVF-ET,but positive semen mycoplasma will reduce the rate of high-quality embryos and the number of transferred embryos.

关 键 词：精液 人型支原体 体外受精 胚胎发育 

分 类 号：R714.8[医药卫生—妇产科学]