2种表观扩散系数值在预测中至低分化直肠腺癌病理类型中的价值  

The value of two apparent diffusion coefficient values in predicting the pathological types of moderately and poorly differentiated rectal adenocarcinoma

作　　者：郑欣 周慧 唐秋 文明[2] ZHENG Xin;ZHOU Hui;TANG Qiu;WEN Ming(Department of Radiology,Chongqing Tongnan Hospital of Traditional Chinese Medicine,Chongqing 402660,China;Department of Radiology,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China)

机构地区：[1]重庆市潼南区中医院放射科,重庆402660 [2]重庆医科大学附属第一医院放射科,重庆400016

出　　处：《实用放射学杂志》2023年第12期1976-1979,共4页Journal of Practical Radiology

基　　金：重庆市潼南区2021年实施项目(TK-2021-18)。

摘　　要：目的探讨2种测量方法获得的直肠癌病灶表观扩散系数(ADC)值对预测中至低分化直肠腺癌病理类型的价值。方法将41例患者依据分化程度分为中分化组和低分化组,并采用直接测量法和最小ADC值法分别测量肿块的ADC值,分析ADC值对预测中至低分化直肠腺癌的效能。结果2种测量方法获得直肠腺癌肿块ADC值,中分化组和低分化组间均存在差异(P<0.01)。ADC值预测中至低分化直肠腺癌效能:直接测量法的曲线下面积(AUC)为0.753,敏感性和特异性分别为96.67%和63.64%;最小ADC值法的AUC为0.838,敏感性和特异性分别为76.67%和81.82%。直接测量法所得ADC值与其病理特征呈正相关(r=0.519,P<0.01);最小ADC值法所得ADC值与其病理特征呈正相关(r=0.391,P<0.05)。结论利用ADC值判断中至低分化直肠腺癌病理类型,直接测量法比最小ADC值法的综合临床价值更大。Objective To explore the apparent diffusion coefficient(ADC)value of rectal cancer lesions obtained by two measurement methods in predicting the pathological types of moderately and poorly differentiated rectal adenocarcinoma.Methods A total of 41 patients were divided into moderately differentiated group and poorly differentiated group according to degrees of differentiation.Direct measurement method and minimum ADC value method were used to measure the ADC value of the tumor,and the effectiveness of the ADC value in predicting moderately and poorly differentiated rectal adenocarcinoma was analyzed.Results The ADC values of rectal adenocarcinoma tumor obtained by two different measurement methods were different between the moderately and poorly differentiated groups(P<0.01).The area under the curve(AUC)of the direct measurement method was 0.753,and the sensitivity and specificity were 96.67%and 63.64%,respectively.The AUC of the minimum ADC value method was 0.838,the sensitivity and specificity were 76.67%and 81.82%,respectively.The ADC value obtained by direct measurement method was positively correlated with its pathological characteristics(r=0.519,P<0.01)and that by the minimum ADC value method was positively correlated with its pathological characteristics(r=0.391,P<0.05).Conclusion The pathological types of moderately and poorly differentiated rectal adenocarcinoma is determined by ADC value.It is found that the direct measurement method has more greater comprehensive clinical value than the minimum ADC value method.

关 键 词：磁共振成像 表观扩散系数 直肠腺癌 组织学分级 

分 类 号：R445.2[医药卫生—影像医学与核医学] R735.37[医药卫生—诊断学] R446.8[医药卫生—临床医学]