全身振动对绝经后骨质疏松妇女治疗效果的Meta分析  

The effects of whole-body vibration on postmenopausal women with osteoporosis:a Meta-analysis

作　　者：于姗[1] 黑静友[2] 陈媛媛 高呈飞 Yu Shan;Hei Jingyou;Chen Yuanyuan;Gao Chengfei(Department of Endocrinology,The Second People’s Hospital of Liaocheng,Liaocheng 252699,China;Department of Joint Surgery,The Second People’s Hospital of Liaocheng,Liaocheng 252699,China;Department of Neurosurgery,The Second People’s Hospital of Liaocheng,Liaocheng 252699,China;Deparment of Rehabilitation Medicine,The Affiliated Hospital of Qingdao University,Qingdao 266001,China)

机构地区：[1]聊城市第二人民医院内分泌科,聊城252699 [2]聊城市第二人民医院关节外科,聊城252699 [3]聊城市第二人民医院神经外科,聊城252699 [4]青岛大学附属医院康复医学科,青岛266001

出　　处：《中华生物医学工程杂志》2023年第5期511-517,共7页Chinese Journal of Biomedical Engineering

基　　金：山东省自然科学基金(ZR2021QH062)。

摘　　要：目的系统评价全身振动(WBV)疗法对绝经后骨质疏松(PMOP)妇女的治疗效果。方法检索中国知网、万方、维普、PubMed、EMBASE、The Cochrane Library、Web of science等数据库,限定检索时间从数据库建立到2022年12月。筛选符合纳入标准的文献并进行数据提取,采用STATA软件进行meta分析。结果最终纳入10项随机对照研究,共计677名患者。Meta分析结果显示:WBV可以显著提高PMOP妇女的腰椎骨密度(BMD)[加权均数差(WMD)=0.024,95%CI:0.002~0.045,P=0.032]、股骨颈BMD(加权均数差(WMD=0.040,95%CI:0.017~0.063,P=0.001)及疼痛评分[标准化均数差(SMD)=-0.786,95%CI:-1.300~-0.272,P=0.002)],但对患者脂肪质量(WMD=1.028,95%CI:-4.811~2.755,P=0.572)、肌肉质量(WMD=0.632,95%CI:-1.437~2.700,P=0.563)无显著作用。结论WBV训练能够提高PMOP妇女BMD并减轻疼痛,但对患者脂肪及肌肉含量无影响。Objective To comprehensively evaluate the therapeutic effects of whole-body vibration(WBV)training on women with postmenopausal osteoporosis(PMOP).Methods The CNKI,Wanfang,VIP,PubMed,EMBASE,Cochrane Library,Web of Science databases were searched from database establishment to December 2022.Two independent researchers screened the articles and extracted data according to the inclusion and exclusion criteria.The data were extracted for meta-analysis using STATA software.Results Ten randomized controlled trials with a total of 677 patients were included.The meta-analysis results showed that WBV can significantly increase lumbar spine bone mineral density(BMD)(WMD=0.024,95%CI:0.002~0.045,P=0.032),femoral neck BMD(WMD=0.040,95%CI:0.017~0.063,P=0.001)and reduce pain score(SMD=-0.786,95%CI:-1.300~-0.272,P=0.002)in women with PMOP,but has no significant effect on patient’fat mass(WMD=1.028,95%CI:-4.811~2.755,P=0.572)and muscle mass(WMD=0.632,95%CI:-1.437~2.700,P=0.563).Conclusions WBV training can improve BMD and relieve pain in women with PMOP,but has no effect on patients’fat mass and muscle mass.

关 键 词：绝经后骨质疏松 全身振动 骨密度 META分析 随机对照试验 

分 类 号：R580[医药卫生—内分泌]