非高血糖性糖尿病酮症酸中毒的诱因及发病机制研究进展  

Research progress on inducement and pathogenesis of euglycemic diabetic ketoacidosis

作　　者：韩利民 刘丹 胡蕖 刘娇 HAN Limin;LIU Dan;HU Qu;LIU Jiao(Department of Endocrinology,Changshou District People’s Hospital,Chongqing 401220,China)

机构地区：[1]重庆市长寿区人民医院内分泌内科,重庆401220

出　　处：《重庆医学》2024年第2期297-301,共5页Chongqing medicine

基　　金：2021年重庆市长寿区科技计划项目(CS2021032)。

摘　　要：非高血糖性糖尿病酮症酸中毒(euDKA)是一种较为罕见的急性代谢紊乱综合征,其特征包括高阴离子间隙的代谢性酸中毒,血酮或尿酮阳性,血糖<13.9 mmol/L。因其血糖水平不高,euDKA在临床工作中容易被漏诊或延迟治疗,最终造成严重后果。近年已有较多euDKA的病例报道,但其诱因及发病机制尚不完全清楚。该文就euDKA的常见诱因及发病机制做一综述。Euglycemic diabetic ketoacidosis(euDKA)is a rare acute metabolic disorder syndrome,its characteristics include metabolic acidosis with a high anion gap,positive ketones in blood or urine,and blood glucose<13.9 mmol/L.Due to low blood sugar level,euDKA is easy to be missed or delayed treatment in clinical work,resulting in serious consequences.In recent years,many cases of euDKA have been reported,but its inducements and pathogenesis are not fully understood.This article reviews the common inducements and pathogenesis of euDKA.

关 键 词：非高血糖性糖尿病酮症酸中毒 钠-葡萄糖协同转运蛋白2抑制剂 低碳水化合物生酮饮食 诱因 机制 综述 

分 类 号：R587.2[医药卫生—内分泌]