夫西地酸滴眼液联合鱼腥草滴眼液在细菌性结膜炎患者中的应用研究  

A Study on the Application of Fusidic Acid Eye Drops Combined with Yuxingcao Eye Drops in Patients with Bacterial Conjunctivitis

作　　者：周雪营 胡春燕 ZHOU Xueying;HU Chunyan(Department of Ophthalmology,Caoxian People's Hospital,Heze,Shandong Province,274400 China)

机构地区：[1]曹县人民医院眼科,山东菏泽274400

出　　处：《世界复合医学》2023年第11期130-133,共4页World Journal of Complex Medicine

摘　　要：目的分析细菌性结膜炎(bacterial conjunctivitis,BC)患者应用夫西地酸滴眼液联合鱼腥草滴眼液治疗取得的效果。方法随机选取2022年7月—2023年6月曹县人民医院就诊的90例BC患者,按照随机数表法分为研究组(n=45)和对照组(n=45)。对照组采用夫西地酸滴眼液治疗,研究组在对照组基础上联用鱼腥草滴眼液治疗。对比两组临床疗效、SchirmerⅠ试验、泪膜破裂时间(break up time,BUT)、中医证候积分以及不良反应。结果与对照组总有效率82.22%相比,研究组总有效率97.78%更高,差异有统计学意义(χ^(2)=4.444,P<0.05)。治疗后,与对照组结果相比,研究组SchirmerⅠ试验、BUT指标更高,中医证候积分更低,差异有统计学意义(P<0.05)。两组不良反应发生率相比,差异无统计学意义(P>0.05)。结论BC患者应用夫西地酸滴眼液联合鱼腥草滴眼液治疗效果确切,能够有效改善患者的症状与泪液分泌指标,安全性佳。Objective To analyze the effect achieved by the application of fusidic acid eye drops combined with Yuxingcao eye drops in the treatment of patients with bacterial conjunctivitis(BC).Methods A total of 90 BC patients treated in Caoxian People's Hospital from July 2022 to June 2023 were randomly selected and divided into study group(n=45)and control group(n=45)according to random number table method.The control group was treated with fusidic acid eye drops,and the study group was treated with Houttuynia eye drops based on the control group.The clinical efficacy,SchirmerⅠtest,tear film break up time(BUT),TCM syndrome score and adverse reactions were compared between the two groups.Results Compared with 82.22%in the control group,the total effective rate of the study group was 97.78%,the difference was statistically significant(χ^(2)=4.444,P<0.05).After treatment,compared with the control group,the SchirmerⅠtest and BUT index of the study group were higher,and the TCM syndrome score was lower,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The application of fusidic acid eye drops combined with Yuxingcao eye drops in BC patients has a precise treatment effect,which can effectively improve the symptoms and tear secretion index of the patients,with good safety.

关 键 词：夫西地酸滴眼液 鱼腥草滴眼液 细菌性结膜炎 

分 类 号：R998[医药卫生—毒理学]