芪苈强心胶囊联合尼可地尔治疗慢性肺心病伴冠心病心衰患者的效果  

Qili Qiangxin Capsule Combined with Nicorandil in the Treatment of Patients with Chronic Pulmonary Heart Disease Accompanied by Coronary Heart Disease and Heart Failure

作　　者：熊云志 罗宗梅 徐菱 XIONG Yunzhi;LUO Zongmei;XU Ling(Department of Cardiovascular Medicine,Yantian District People's Hospital,Shenzhen,Guangdong Province,518081 China;Department of Cardiovascular Medicine,Guiyang Second People's Hospital,Guiyang,Guizhou Province,550081 China;Department of Gynecology,Luohu District People's Hospital,Shenzhen,Guangdong Province,518005 China)

机构地区：[1]深圳市盐田区人民医院心血管内科,广东深圳518081 [2]贵州省贵阳市第二人民医院心血管内科,贵州贵阳550081 [3]深圳市罗湖区人民医院妇科,广东深圳518005

出　　处：《世界复合医学》2023年第11期134-136,140,共4页World Journal of Complex Medicine

摘　　要：目的综合分析芪苈强心胶囊联合尼可地尔治疗慢性肺源性心脏病(简称慢性肺心病)伴冠心病心力衰竭的临床治疗效果。方法回顾性选取2021年10月—2022年12月深圳市盐田区人民医院收治的60例慢性肺心病伴冠心病心力衰竭患者的临床资料。按照患者入院顺序分为对照组(30例,应用尼可地尔治疗)和研究组(30例,在对照组基础上应用芪苈强心胶囊治疗),比较两组患者的临床治疗有效率、心功能指标及生存质量。结果与对照组比较,研究组临床治疗总有效率(90.00%)更高,差异有统计学意义(χ^(2)=4.706,P<0.05);治疗后,研究组左室射血分数、每搏输出量高于对照组,左室舒张末期内径低于对照组,差异有统计学意义(P<0.05);治疗后,研究组生存质量评分均高于对照组,差异有统计学意义(P<0.05)。结论芪苈强心胶囊联合尼可地尔治疗慢性肺心病伴冠心病心力衰竭患者的临床治疗效果显著。Objective To comprehensively analyze the clinical therapeutic effect of Qili Qiangxin capsule combined with nicorandil in the treatment of chronic pulmonary heart disease(referred to as chronic pulmonary heart disease)with coronary heart failure.Methods The clinical data of 60 patients with chronic pulmonary heart disease with CHD and heart failure treated in Yantian District People's Hospital of Shenzhen from October 2021 to December 2022 were retrospectively selected.Patients were divided into control group(30 cases,treatment with nicodil)and study group(30 cases,treatment with Qiliqiangxin capsule on the basis of control group)according to the order of admission.Clinical treatment effectiveness,cardiac function indexes,quality of life of the two groups were compared.Results Compared with the control group,the total effective rate of the study group(90.00%)was higher,the difference was statistically significant(χ^(2)=4.706,P<0.05).After treatment,the left ventricular ejection fraction and output per beam in the study group were higher than those in the control group,and the left ventricular end-diastolic diameter was lower than that in the control group,the differences were statistically significant(P<0.05).After treatment,the quality of life score of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion The clinical therapeutic effect of Qili Qiangxin capsule combined with nicorandil in the treatment of patients with chronic pulmonary heart disease accompanied by coronary heart failure is remarkable.

关 键 词：芪苈强心胶囊 尼可地尔 慢性肺心病伴冠心病心力衰竭 临床治疗效果 心功能 生存质量 

分 类 号：R541.5[医药卫生—心血管疾病]