经皮封堵术治疗复杂型卵圆孔未闭的疗效分析  

Analysis of the efficacy of percutaneous closure for the treatment of complex patent foramen ovale

作　　者：辛君政 张建卿[2] 王国锋[2] 姬建民 樊宗铭 黄华 XIN Junzheng;ZHANG Jianqing;WANG Guofeng;JI Jianmin;FAN Zongming;HUANG Hua(Xinxiang Medical University,Xinxiang 450000,China)

机构地区：[1]新乡医学院,450000 [2]郑州市第七人民医院 [3]河南省胸科医院

出　　处：《心肺血管病杂志》2024年第1期46-51,共6页Journal of Cardiovascular and Pulmonary Diseases

摘　　要：目的:分析长隧道型或合并房间隔膨出瘤(atrial septal aneurysm,ASA)的卵圆孔未闭(patent foramen oval,PFO)经皮封堵术后的临床疗效及相关影响因素。方法:选取2021年3月至2022年8月期间,于郑州市第七人民医院行PFO封堵术的24例长隧道型或合并ASA的PFO患者。在术前、术后3个月、术后6个月对患者进行随访观察,记录患者偏头痛、头晕等临床症状的程度及持续时间,以头痛影响测定评分-6(headache impact test-6,HIT-6)和头晕视觉模拟量表(visual analogue scale,VAS)表示。结果:术后随访,此类PFO患者术后3个月临床症状缓解有效的18例(75.0%),术后6个月临床症状缓解有效的20例(83.3%),封堵术前术后HIT-6评分及头晕VAS评分均显著降低(P<0.01)。6例术前有脑血管事件发生的患者,术后6个月均无再发脑血管事件。结论:长隧道型或合并ASA的PFO患者,行PFO封堵术可以有效缓解相关临床症状,改善生命质量,同时手术安全性较高,具有一定临床指导意义。Objective:To analyze the clinical efficacy and related influencing factors after percutaneous closure of patent foramen oval(PFO)with long tunnel or associated atrial septal aneurysm(ASA).Methods:A total of 24 patients with PFO of long tunnel type or combined with ASA who underwent PFO occlusion surgery at Zhengzhou Seventh People's Hospital between March 2021 and August 2022 were selected.Follow-up observations were conducted before surgery,3 months after surgery,and 6 months after surgery to record the degree and duration of patients'symptoms,including migraine,dizziness,as expressed by headache impact test-6(HIT-6)and dizziness visual analogue scale(VAS).Results:Analyzing the data from the follow-up after percutaneous closure,18 patients(75.0%)had effective clinical symptoms relief 3 months after surgery,and 20 patients(83.3%)had effective clinical symptoms relief 6 months after surgery.Both the HIT-6 score and the dizziness VAS score were significantly reduced before and after the closure surgery(P<0.01).Six patients who had a history of cerebral vascular events before surgery were free of recurrent cerebral vascular events after six months.Conclusions:PFO closure can effectively alleviate related clinical symptoms and improve quality of life in patients with long tunnel type or ASA patients,and the safety of surgery is high,which has certain clinical guiding significance.

关 键 词：卵圆孔未闭 房间隔膨出瘤 右向左分流 偏头痛 头晕 

分 类 号：R54[医药卫生—心血管疾病]